Latest & greatest articles for anticoagulation

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Top results for anticoagulation

1. Covid-19 patients who are not hospitalised: anticoagulation is rarely justified (Full text)

Covid-19 patients who are not hospitalised: anticoagulation is rarely justified Prescrire IN ENGLISH - Spotlight ''Covid-19 patients who are not hospitalised: anticoagulation is rarely justified'', 24 September 2020 {1} {1} {1} | | > > > Covid-19 patients who are not hospitalised: anticoagulation is rarely justified Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |    (...) |  Spotlight Covid-19 patients who are not hospitalised: anticoagulation is rarely justified NEWS UPDATE The risk of thromboembolism in patients with a mild to moderate form of covid-19 is unclear and probably varies greatly between patients. Is anticoagulation justified to prevent deep vein thrombosis in patients with covid-19 who are not hospitalised? Arterial or venous thromboembolism is a common complication in patients hospitalised in intensive care for a severe form of covid-19

2020 Prescrire PubMed abstract

2. The increased risk of bleeding due to drug-drug interactions in patients administered direct oral anticoagulants

The increased risk of bleeding due to drug-drug interactions in patients administered direct oral anticoagulants The increased risk of bleeding due to drug-drug interactions in patients administered direct oral anticoagulants - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get (...) to drug-drug interactions in patients administered direct oral anticoagulants , , , , , , , Affiliations Expand Affiliations 1 Department of Internal Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. 2 SCH Biomedical Informatics Research Unit, Seoul, Republic of Korea. 3 Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea. 4 Department of Pediatrics

2020 EvidenceUpdates

3. Andexanet alfa (Ondexxya) - For adult patients treated with a direct factor Xa (FXa) inhibitor (apixaban or rivaroxaban) when reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding.

Andexanet alfa (Ondexxya) - For adult patients treated with a direct factor Xa (FXa) inhibitor (apixaban or rivaroxaban) when reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding. 1 Published 7 September 2020 1 SMC2273 andexanet alfa 200 mg powder for solution for infusion (Ondexxya®) Portola Pharmaceuticals UK Ltd. 07 August 2020 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and, following review by the SMC executive (...) , advises NHS Boards and Area Drug and Therapeutics Committees on its use in NHSScotland. The advice is summarised as follows: ADVICE: following a full submission andexanet alfa (Ondexxya®) is accepted for use within NHSScotland on an interim basis subject to ongoing evaluation and future reassessment. Indication under review: For adult patients treated with a direct factor Xa (FXa) inhibitor (apixaban or rivaroxaban) when reversal of anticoagulation is needed due to life-threatening or uncontrolled

2020 Scottish Medicines Consortium

4. Recurrent venous thromboembolism during anticoagulation with edoxaban or warfarin: A post hoc analysis of the Hokusai-VTE trial

Recurrent venous thromboembolism during anticoagulation with edoxaban or warfarin: A post hoc analysis of the Hokusai-VTE trial Recurrent venous thromboembolism during anticoagulation with edoxaban or warfarin: A post hoc analysis of the Hokusai-VTE trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging (...) . Recurrent venous thromboembolism during anticoagulation with edoxaban or warfarin: A post hoc analysis of the Hokusai-VTE trial , , , , Affiliations Expand Affiliations 1 Dept. of Medicine I, Medical University of Vienna, Austria. Electronic address: sabine.eichinger@meduniwien.ac.at. 2 Daiichi-Sankyo Pharma Development, Basking Ridge, NJ, United States of America. 3 Dept. of Medicine I, Medical University of Vienna, Austria. PMID: 32750571 DOI: Item in Clipboard Recurrent venous thromboembolism during

2020 EvidenceUpdates

5. The Association between Oral Anticoagulants and Cancer Incidence among Individuals with Nonvalvular Atrial Fibrillation

The Association between Oral Anticoagulants and Cancer Incidence among Individuals with Nonvalvular Atrial Fibrillation The Association between Oral Anticoagulants and Cancer Incidence among Individuals with Nonvalvular Atrial Fibrillation - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving (...) Anticoagulants and Cancer Incidence among Individuals with Nonvalvular Atrial Fibrillation , , , , Affiliations Expand Affiliations 1 Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, Canada. 2 Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada. 3 Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada. 4 Département de Médecine Générale, Université de Nantes, Nantes

2020 EvidenceUpdates

6. Direct oral anticoagulant versus low-molecular-weight heparin for treatment of venous thromboembolism in cancer patients: An updated meta-analysis of randomized controlled trials

Direct oral anticoagulant versus low-molecular-weight heparin for treatment of venous thromboembolism in cancer patients: An updated meta-analysis of randomized controlled trials Direct oral anticoagulant versus low-molecular-weight heparin for treatment of venous thromboembolism in cancer patients: An updated meta-analysis of randomized controlled trials - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search (...) Thromb Res Actions . 2020 Jun 18;194:57-65. doi: 10.1016/j.thromres.2020.06.025. Online ahead of print. Direct oral anticoagulant versus low-molecular-weight heparin for treatment of venous thromboembolism in cancer patients: An updated meta-analysis of randomized controlled trials , , , , , , , , Affiliations Expand Affiliations 1 Hurley Medical Center, Department of Internal Medicine, Flint, MI, USA; Michigan State University, College of Human Medicine, East Lansing, MI, USA. 2 Lebanese University

2020 EvidenceUpdates

7. Should We Reintroduce Previous Venous Thromboembolism Into Decision-Making for Anticoagulation in Atrial Fibrillation?

Should We Reintroduce Previous Venous Thromboembolism Into Decision-Making for Anticoagulation in Atrial Fibrillation? Should We Reintroduce Previous Venous Thromboembolism Into Decision-Making for Anticoagulation in Atrial Fibrillation? - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving (...) We Reintroduce Previous Venous Thromboembolism Into Decision-Making for Anticoagulation in Atrial Fibrillation? , , , , , Affiliations Expand Affiliations 1 Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health, Aalborg University, Denmark; Department of Medicine, North Denmark Regional Hospital, Hjørring, Denmark. Electronic address: t.overvad@rn.dk. 2 Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health, Aalborg University, Denmark

2020 EvidenceUpdates

8. Left Atrial Appendage Closure Versus Direct Oral Anticoagulants in High-Risk Patients With Atrial Fibrillation

Left Atrial Appendage Closure Versus Direct Oral Anticoagulants in High-Risk Patients With Atrial Fibrillation Left Atrial Appendage Closure Versus Direct Oral Anticoagulants in High-Risk Patients With Atrial Fibrillation - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get (...) there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation J Am Coll Cardiol Actions . 2020 Jun 30;75(25):3122-3135. doi: 10.1016/j.jacc.2020.04.067. Left Atrial Appendage Closure Versus Direct Oral Anticoagulants in High-Risk Patients With Atrial Fibrillation

2020 EvidenceUpdates

9. Management of Bleeding in Patients on Oral Anticoagulants

Management of Bleeding in Patients on Oral Anticoagulants EXPERT CONSENSUS DECISION PATHWAY 2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants A Report of the American College of Cardiology Solution Set Oversight Committee Writing Committee* Gordon F. Tomaselli, MD, FACC, Chair Kenneth W. Mahaffey, MD, FACC, Vice Chair Adam Cuker, MD, MS Paul P. Dobesh, PHARMD John U. Doherty, MD, FACC John W. Eikelboom, MBBS Roberta Florido, MD, MHS Ty J (...) . OAC Reversal Agents in Development 608 5.7. Considerations for Restarting Anticoagulation.. 608 Figure 4. Considerations for Restarting Anticoagulation ..609 5.7.1. ShouldAnticoagulationBeRestarted? ..608 Table 6. Original Indications for Anti- coagulation With High Thrombotic Risk .. 610 5.7.2. Timing of Anticoagulation Reinitiation ..609 Figure 5. Restart of Anticoagulation 611 Figure 6. Delaying Restart of Anticoagulation . 612 5.7.2. Patient Engagement in Restarting Anticoagulation ... .. 610

2020 American College of Cardiology

10. Role of Combination Antiplatelet and Anticoagulation Therapy in Diabetes Mellitus and Cardiovascular Disease: Insights From the COMPASS Trial (Full text)

Role of Combination Antiplatelet and Anticoagulation Therapy in Diabetes Mellitus and Cardiovascular Disease: Insights From the COMPASS Trial Role of Combination Antiplatelet and Anticoagulation Therapy in Diabetes Mellitus and Cardiovascular Disease: Insights From the COMPASS Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable (...) Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Circulation Actions . 2020 Jun 9;141(23):1841-1854. doi: 10.1161/CIRCULATIONAHA.120.046448. Epub 2020 Mar 28. Role of Combination Antiplatelet and Anticoagulation Therapy in Diabetes Mellitus and Cardiovascular Disease: Insights From the COMPASS Trial , , , , , , , , , , , , , , , , , , , , Collaborators, Affiliations Expand Collaborators COMPASS Steering

2020 EvidenceUpdates PubMed abstract

11. Direct Oral Anticoagulants for the Treatment of Acute Venous Thromboembolism Associated with Cancer: A Systematic Review and Meta-Analysis (Full text)

Direct Oral Anticoagulants for the Treatment of Acute Venous Thromboembolism Associated with Cancer: A Systematic Review and Meta-Analysis Direct Oral Anticoagulants for the Treatment of Acute Venous Thromboembolism Associated with Cancer: A Systematic Review and Meta-Analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable (...) Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Thromb Haemost Actions . 2020 Jul;120(7):1128-1136. doi: 10.1055/s-0040-1712098. Epub 2020 May 4. Direct Oral Anticoagulants for the Treatment of Acute Venous Thromboembolism Associated with Cancer: A Systematic Review and Meta-Analysis , , , , , , , , , , , Affiliations Expand Affiliations 1 Internal Vascular and Emergency Medicine - Stroke Unit, University

2020 EvidenceUpdates PubMed abstract

12. Direct-acting oral anticoagulants (DOACs): reminder of bleeding risk, including availability of reversal agents

Direct-acting oral anticoagulants (DOACs): reminder of bleeding risk, including availability of reversal agents Direct-acting oral anticoagulants (DOACs): reminder of bleeding risk, including availability of reversal agents - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance (...) and support Direct-acting oral anticoagulants (DOACs): reminder of bleeding risk, including availability of reversal agents Remain vigilant for signs and symptoms of bleeding complications during treatment with DOACs (apixaban, dabigatran, edoxaban, rivaroxaban), especially in patients with increased bleeding risks. Specific reversal agents are available for dabigatran (Praxbind▼, idarucizumab), and apixaban and rivaroxaban (Ondexxya▼, andexanet alfa). Published 29 June 2020 From: Therapeutic area

2020 MHRA Drug Safety Update

13. Use of Anticoagulation in Patients with COVID-19 Infection (Full text)

Use of Anticoagulation in Patients with COVID-19 Infection Use of Anticoagulation in Patients with COVID-19 Infection - CanadiEM Use of Anticoagulation in Patients with COVID-19 Infection In by Johnny Huang June 18, 2020 Introduction The novel coronavirus, known as COVID-19, was originally reported in a cluster of pneumonia cases in Wuhan (China) near the end of 2019 ​1​ . Over the next 6 months, COVID-19 has emerged as the world’s newest pandemic disease with over 7 million cases worldwide ​1 (...) and reduced fibrinogen levels, the distinguishing feature of COVID-19 pertains to thrombosis formation and inflammation without significant consumption of coagulation markers ​5​ . A case-series study showed an increased risk for VTE, mostly pulmonary embolism, among intensive care unit (ICU) patients with COVID-19-associated acute respiratory distress syndrome (ARDS) than those with non-COVID-19 ARDS, despite being on prophylactic anticoagulation ​9​ . Similar studies showed an incidence of VTE up to 30

2020 CandiEM PubMed abstract

14. Quality of life after switching from well-controlled vitamin K antagonist to direct oral anticoagulant: Little to GAInN (Full text)

Quality of life after switching from well-controlled vitamin K antagonist to direct oral anticoagulant: Little to GAInN Quality of Life After Switching From Well-Controlled Vitamin K Antagonist to Direct Oral Anticoagulant: Little to GAInN - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National (...) : Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Thromb Res Actions . 2020 Jun;190:69-75. doi: 10.1016/j.thromres.2020.04.007. Epub 2020 Apr 14. Quality of Life After Switching From Well-Controlled Vitamin K Antagonist to Direct Oral Anticoagulant: Little to GAInN , , , , , Affiliations Expand Affiliations 1 Department of Hematology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Certe Thrombosis

2020 EvidenceUpdates PubMed abstract

15. Psychotropic Drugs and Outcome in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism

Psychotropic Drugs and Outcome in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism Psychotropic Drugs and Outcome in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library of Medicine National Center (...) Link Copy Actions Cite Share Permalink Copy Page navigation Thromb Haemost Actions . 2020 Apr;120(4):620-626. doi: 10.1055/s-0040-1708482. Epub 2020 Apr 14. Psychotropic Drugs and Outcome in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Internal Medicine and Emergency, Parc Sanitari Sant Joan de Déu-Hospital General, Barcelona, Spain. 2 Department of Haematology and Bone Marrow Transplantation, Rambam Health

2020 EvidenceUpdates

16. Meta-Analysis Comparing Direct Oral Anticoagulants Versus Warfarin in Morbidly Obese Patients With Atrial Fibrillation

Meta-Analysis Comparing Direct Oral Anticoagulants Versus Warfarin in Morbidly Obese Patients With Atrial Fibrillation Meta-Analysis Comparing Direct Oral Anticoagulants Versus Warfarin in Morbidly Obese Patients With Atrial Fibrillation - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library (...) displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Am J Cardiol Actions . 2020 Jul 1;126:23-28. doi: 10.1016/j.amjcard.2020.03.048. Epub 2020 Apr 8. Meta-Analysis Comparing Direct Oral Anticoagulants Versus Warfarin in Morbidly Obese Patients With Atrial Fibrillation , , , Affiliations Expand Affiliations 1 Department of Clinical Pharmacy, West Virginia University School of Pharmacy, Morgantown, West Virginia. Electronic address: kazuhiko.kido0322@gmail.com. 2

2020 EvidenceUpdates

17. The Effect of Warfarin Administration Time on Anticoagulation Stability (INRange): A Pragmatic Randomized Controlled Trial (Full text)

The Effect of Warfarin Administration Time on Anticoagulation Stability (INRange): A Pragmatic Randomized Controlled Trial The Effect of Warfarin Administration Time on Anticoagulation Stability (INRange): A Pragmatic Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National (...) Permalink Copy Page navigation Ann Fam Med Actions . 2020 Jan;18(1):42-49. doi: 10.1370/afm.2488. The Effect of Warfarin Administration Time on Anticoagulation Stability (INRange): A Pragmatic Randomized Controlled Trial , , , , , , , Affiliations Expand Affiliations 1 Department of Family Medicine, University of Alberta, Edmonton, Alberta, Canada scott.garrison@ualberta.ca. 2 Department of Family Medicine, University of Alberta, Edmonton, Alberta, Canada. 3 Department of Anesthesiology, Pharmacology

2020 EvidenceUpdates PubMed abstract

18. Comparing Major Bleeding Risk in Outpatients With Atrial Fibrillation or Flutter by Oral Anticoagulant Type (from the National Cardiovascular Disease Registry`s Practice Innovation and Clinical Excellence Registry)

Comparing Major Bleeding Risk in Outpatients With Atrial Fibrillation or Flutter by Oral Anticoagulant Type (from the National Cardiovascular Disease Registry`s Practice Innovation and Clinical Excellence Registry) Comparing Major Bleeding Risk in Outpatients With Atrial Fibrillation or Flutter by Oral Anticoagulant Type (From the National Cardiovascular Disease Registry's Practice Innovation and Clinical Excellence Registry) - PubMed This site needs JavaScript to work properly. Please enable (...) when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Am J Cardiol Actions . 2020 May 15;125(10):1500-1507. doi: 10.1016/j.amjcard.2020.02.028. Epub 2020 Mar 5. Comparing Major Bleeding Risk in Outpatients With Atrial Fibrillation or Flutter by Oral Anticoagulant Type (From the National Cardiovascular Disease Registry's Practice Innovation and Clinical

2020 EvidenceUpdates

19. Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation. (Abstract)

Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation. The roles of anticoagulation alone or with an antiplatelet agent after transcatheter aortic-valve implantation (TAVI) have not been well studied.We performed a randomized trial of clopidogrel in patients undergoing TAVI who were receiving oral anticoagulation for appropriate indications. Patients were assigned before TAVI in a 1:1 ratio not to receive clopidogrel or to receive clopidogrel for 3 months (...) from cardiovascular causes, ischemic stroke, or myocardial infarction (secondary composite 2), both tested for noninferiority (noninferiority margin, 7.5 percentage points) and superiority.Bleeding occurred in 34 of the 157 patients (21.7%) receiving oral anticoagulation alone and in 54 of the 156 (34.6%) receiving oral anticoagulation plus clopidogrel (risk ratio, 0.63; 95% confidence interval [CI], 0.43 to 0.90; P = 0.01); most bleeding events were at the TAVI access site. Non-procedure-related

2020 NEJM

20. Current practice of anticoagulant in the treatment of splanchnic vein thrombosis secondary to acute pancreatitis. (Abstract)

Current practice of anticoagulant in the treatment of splanchnic vein thrombosis secondary to acute pancreatitis. Severe acute pancreatitis is a common diagnosis in emergency general surgery and can be a cause of significant morbidity and mortality. A consequence of severe acute pancreatitis is thrombus in the splanchnic veins. These thrombi can potentially lead to bowel ischemia or hepatic failure. However, another complication of severe acute pancreatitis is retroperitoneal bleeding (...) researchers. Any disagreement was reviewed by a third independent researcher. Primary outcome was reestablishment of flow in the thrombosed vein versus bleeding complications.Of 1462 papers assessed, a total of 16 papers were eligible for inclusion. There were no randomized controlled trials, 2 were case series, 5 retrospective single-center studies and 9 case reports. There were a total of 198 patients in these studies of whom 92 (46.5%) received anticoagulation therapy. The rates of recanalization

2020 Hepatobiliary & pancreatic diseases international : HBPD INT