Latest & greatest articles for anxiety

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on anxiety or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on anxiety and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Anxiety

Anxiety is the subjectively feelings of dread over anticipated events and it is different from fear. Clinical anxiety is a group of mental disorders with generalised anxiety disorder (GAD) being the most common (approximately 22% of primary care attendances for anxiety are classed as GAD). Overall, there is a lifetime prevalence rate of 4-7%. Anxiety can be caused by a number of factors typically classified as environmental surroundings and genetic.

In the past few decades anxiety research has significantly increased. In 2000 there were approximately 430 trials looking at anxiety and by 2015 to over 1,000. This has allowed medical professionals to develop and improve accurate diagnosis and treatments in patients suffering from the condition.

Anxiety is normal in uncomfortable environments or stressful situations. However, some individuals experience intense and persistent amounts of anxiety which needs to be kept under control. Treatments include pharmaceuticals such as SSRIs, benzodiazepines, pregabalin and gabapentin. Other therapies include CBT, acceptance and commitment therapy, and motivational interviewing.

Trip has all the latest evidence relating to treatments for anxiety, this includes systematic reviews, clinical guidelines, controlled trials, evidence-based synopses, case reports and clinical Q&As.

Top results for anxiety

1. The effectiveness of aromatherapy on preoperative anxiety in adults: A systematic review and meta-analysis of randomized controlled trials

The effectiveness of aromatherapy on preoperative anxiety in adults: A systematic review and meta-analysis of randomized controlled trials The effectiveness of aromatherapy on preoperative anxiety in adults: A systematic review and meta-analysis of randomized controlled trials - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID (...) /j.ijnurstu.2020.103747. Online ahead of print. The effectiveness of aromatherapy on preoperative anxiety in adults: A systematic review and meta-analysis of randomized controlled trials , , , , , , , Affiliations Expand Affiliations 1 School of Nursing, Jilin University, No. 965 Xinjiang, Street, Changchun, Jilin Province 130021, China. 2 Second Hospital of Jilin University, Changchun, China. 3 School of Nursing, Jilin University, No. 965 Xinjiang, Street, Changchun, Jilin Province 130021, China

2020 EvidenceUpdates

2. Active and Passive Distraction Interventions in a Pediatric Emergency Department to Reduce the Pain and Anxiety During Venous Blood Sampling: A Randomized Clinical Trial

Active and Passive Distraction Interventions in a Pediatric Emergency Department to Reduce the Pain and Anxiety During Venous Blood Sampling: A Randomized Clinical Trial Active and Passive Distraction Interventions in a Pediatric Emergency Department to Reduce the Pain and Anxiety During Venous Blood Sampling: A Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History (...) Actions . 2020 Jul 22;S0099-1767(20)30153-7. doi: 10.1016/j.jen.2020.05.004. Online ahead of print. Active and Passive Distraction Interventions in a Pediatric Emergency Department to Reduce the Pain and Anxiety During Venous Blood Sampling: A Randomized Clinical Trial , PMID: 32711948 DOI: Item in Clipboard Active and Passive Distraction Interventions in a Pediatric Emergency Department to Reduce the Pain and Anxiety During Venous Blood Sampling: A Randomized Clinical Trial Aylin Arıkan et al. J

2020 EvidenceUpdates

3. Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial

Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced (...) . doi: 10.1192/bjp.2020.138. Online ahead of print. Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial , , , , , , , Affiliations Expand Affiliations 1 Institute of Life and Human Sciences, University of Liverpool, UK; and Human Development Research Foundation, Islamabad, Pakistan. 2 Human Development Research Foundation, Islamabad, Pakistan. 3 Institute of Life and Human Sciences, University

2020 EvidenceUpdates

4. Dose Timing of D-Cycloserine to Augment Exposure Therapy for Social Anxiety Disorder: A Randomized Clinical Trial (Full text)

Dose Timing of D-Cycloserine to Augment Exposure Therapy for Social Anxiety Disorder: A Randomized Clinical Trial Dose Timing of D-Cycloserine to Augment Exposure Therapy for Social Anxiety Disorder: A Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library (...) displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation JAMA Netw Open Actions . 2020 Jun 1;3(6):e206777. doi: 10.1001/jamanetworkopen.2020.6777. Dose Timing of D-Cycloserine to Augment Exposure Therapy for Social Anxiety Disorder: A Randomized Clinical Trial , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Institute for Mental Health Research, Department of Psychology, The University of Texas at Austin, Austin. 2 Department of Psychiatry, Rush

2020 EvidenceUpdates PubMed abstract

5. Screening for Anxiety in Adolescent and Adult Women: A Systematic Review for the Women's Preventive Services Initiative. (Abstract)

Screening for Anxiety in Adolescent and Adult Women: A Systematic Review for the Women's Preventive Services Initiative. Anxiety disorders are infrequently recognized during routine health care even though they are common in adolescent girls and adult women.To evaluate evidence on the effectiveness of screening for anxiety disorders in primary care in improving symptoms, function, and quality of life; harms of screening; accuracy of screening instruments; and effectiveness and harms (...) of treatments.English-language searches of Ovid MEDLINE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Health and Psychosocial Instruments (1 January 1996 to 4 November 2019); ClinicalTrials.gov (November 2019); and reference lists of studies and reviews.Studies that enrolled adolescent girls and adult women not currently diagnosed with anxiety disorders, including pregnant or postpartum women, and compared clinical outcomes and harms between women who were and were

2020 Annals of Internal Medicine

6. Screening for Anxiety in Adolescent and Adult Women: A Recommendation From the Women's Preventive Services Initiative. (Abstract)

Screening for Anxiety in Adolescent and Adult Women: A Recommendation From the Women's Preventive Services Initiative. The Women's Preventive Services Initiative (WPSI), a national coalition of women's health professional organizations and patient representatives, developed a recommendation on screening for anxiety in adolescent and adult women to improve detection; achieve earlier diagnosis and treatment; and improve health, function, and well-being. The WPSI's recommendations are intended (...) to guide clinical practice and coverage of services for the Health Resources and Services Administration and other stakeholders. The target audience for this recommendation includes all clinicians providing preventive health care to women, particularly in primary care settings. This recommendation applies to women and adolescent girls aged 13 years or older who are not currently diagnosed with anxiety disorders, including pregnant and postpartum women.The WPSI developed this recommendation after

2020 Annals of Internal Medicine

7. Coping With Stress, Anxiety, And Substance Use During Covid-19

Coping With Stress, Anxiety, And Substance Use During Covid-19 Coping With Stress, Anxiety, And Substance Use During Covid-19 [infographic] | Canadian Centre on Substance Use and Addiction Browse and – trusted sources for your information and research needs. Search the CCSA website Search Substances and Addiction SPOTLIGHT Health and Public Safety SPOTLIGHT People and Communities SPOTLIGHT Data Trends SPOTLIGHT About Us SPOTLIGHT Menu Search the CCSA website Search Substances and Addiction (...) SPOTLIGHT Health and Public Safety SPOTLIGHT People and Communities SPOTLIGHT Data Trends SPOTLIGHT About Us SPOTLIGHT Breadcrumb Coping With Stress, Anxiety, And Substance Use During Covid-19 [infographic] Share Infographic Coping With Stress, Anxiety, And Substance Use During Covid-19 [infographic] Publication date: 2020 Author: Canadian Centre on Substance Use and Addiction; Mental Health Commission of Canada Overview of facts, tips and resources to help Canadians cope with stress, anxiety

2020 Canadian Centre on Substance Abuse

8. Effect of Internet vs Face-to-Face Cognitive Behavior Therapy for Health Anxiety: A Randomized Noninferiority Clinical Trial

Effect of Internet vs Face-to-Face Cognitive Behavior Therapy for Health Anxiety: A Randomized Noninferiority Clinical Trial Effect of Internet vs Face-to-Face Cognitive Behavior Therapy for Health Anxiety: A Randomized Noninferiority Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health (...) Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation JAMA Psychiatry Actions . 2020 May 13;e200940. doi: 10.1001/jamapsychiatry.2020.0940. Online ahead of print. Effect of Internet vs Face-to-Face Cognitive Behavior Therapy for Health Anxiety: A Randomized Noninferiority Clinical Trial , , , , , Affiliations Expand Affiliations 1 Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. 2

2020 EvidenceUpdates

9. Coached Mobile App Platform for the Treatment of Depression and Anxiety Among Primary Care Patients: A Randomized Clinical Trial

Coached Mobile App Platform for the Treatment of Depression and Anxiety Among Primary Care Patients: A Randomized Clinical Trial Coached Mobile App Platform for the Treatment of Depression and Anxiety Among Primary Care Patients: A Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes (...) Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation JAMA Psychiatry Actions . 2020 May 20;e201011. doi: 10.1001/jamapsychiatry.2020.1011. Online ahead of print. Coached Mobile App Platform for the Treatment of Depression and Anxiety Among Primary Care Patients: A Randomized Clinical Trial , , , , , , Affiliations Expand Affiliations 1 Center for Behavioral Intervention Technologies, Northwestern University, Chicago, Illinois

2020 EvidenceUpdates

10. Interventions for anxiety in mainstream school-aged children with autism spectrum disorder (ASD) (Full text)

Interventions for anxiety in mainstream school-aged children with autism spectrum disorder (ASD) Interventions for anxiety in mainstream school‐aged children with autism spectrum disorder: A systematic review - Hillman - 2020 - Campbell Systematic Reviews - Wiley Online Library COVID-19 campus closures: see options for to subscribed content. By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open (...) Access Interventions for anxiety in mainstream school‐aged children with autism spectrum disorder: A systematic review Corresponding Author E-mail address: Australian Council for Educational Research, Camberwell, Victoria, Australia Correspondence Petra Lietz, Australian Council for Educational Research, 186B Pulteney Street, Adelaide, SA 5000, Australia. Email: Australian Council for Educational Research, Adelaide, South Australia, Australia Australian Council for Educational Research, Adelaide

2020 Campbell Collaboration PubMed abstract

11. Systematic review of benzodiazepines for anxiety disorders in late life. (Abstract)

Systematic review of benzodiazepines for anxiety disorders in late life. Benzodiazepines are currently the most commonly prescribed medication for the treatment of anxiety in older adults, although there is a dearth of good-quality data on this subject. The aim of this review was to systematically review studies examining the efficacy and tolerability of benzodiazepines for the treatment of anxiety disorders among older adults.The authors conducted a systematic review, searching PubMed, Ovid (...) ) evaluated the titles, abstracts, and full text of the eligible articles. Five studies met the inclusion criteria. Across all studies, benzodiazepines were associated with decreased anxiety at the end of the study period. The limited tolerability data show mild adverse effects from the benzodiazepines studied. Limitations of the trials included limited data on the long-term use of benzodiazepines for anxiety and a preponderance of trials examining generalized anxiety disorder, with relatively less data

2020 Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists

12. The role of exposure in the treatment of anxiety in children and adolescents: protocol of a systematic review and meta-analysis. (Full text)

The role of exposure in the treatment of anxiety in children and adolescents: protocol of a systematic review and meta-analysis. In children and adolescents, anxiety disorders (ADs) are among the most prevalent mental disorders. While there is a solid empirical foundation to support CBT as an evidence-based treatment for childhood ADs, the mechanisms underlying the efficacy of CBT are not well explored. Exposure is assumed to be vital to the efficacy of CBT in ADs, but empirical evidence (e.g (...) ., dismantling studies) showing that exposure is indeed a vital element of effective treatments is relatively scarce. The proposed meta-analysis aims to investigate the role of exposure in reducing symptoms of anxiety among children and adolescents.A systematic search of several electronic databases including PubMed/MEDLINE, PsycINFO, Psyndex plus, Web of Science, Scopus, and EMBASE will be conducted (from inception onwards). We will include randomized and non-randomized clinical trials examining exposure

2020 Systematic reviews PubMed abstract

13. Psychological or educational eHealth interventions on depression, anxiety or stress following preterm birth: a systematic review. (Abstract)

Psychological or educational eHealth interventions on depression, anxiety or stress following preterm birth: a systematic review. Objective: To determine the efficacy and characteristics of psychological or educational eHealth interventions on reducing symptoms of mental illness in parents of preterm or low birthweight infants.Background: Many parents suffer psychological disorders after preterm birth. Computer or mobile application-based interventions are a promising alternative.Methods: We (...) searched seven electronic databases up to January 2020 and included randomised and quasi-randomised controlled trials assessing psychological or educational eHealth interventions in parents of infants born very preterm <32 weeks or with very low birthweight <1500g (primary question), or preterm <37 weeks or with low birthweight <2500g (secondary question). Primary outcomes were measures of depression, anxiety, acute stress disorder or post-traumatic stress disorder. Secondary outcomes included other

2020 Journal of Reproductive and Infant Psychology

14. Digital Mental Health Interventions for Depression, Anxiety, and Enhancement of Psychological Well-Being Among College Students: Systematic Review. (Full text)

Digital Mental Health Interventions for Depression, Anxiety, and Enhancement of Psychological Well-Being Among College Students: Systematic Review. College students are increasingly reporting common mental health problems, such as depression and anxiety, and they frequently encounter barriers to seeking traditional mental health treatments. Digital mental health interventions, such as those delivered via the Web and apps, offer the potential to improve access to mental health treatment.This (...) study aimed to review the literature on digital mental health interventions focused on depression, anxiety, and enhancement of psychological well-being among samples of college students to identify the effectiveness, usability, acceptability, uptake, and adoption of such programs.We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (registration number CRD42018092800), and the search strategy was conducted by a medical research

2020 Journal of medical Internet research PubMed abstract

15. Defining Depression and Anxiety in Individuals With Rheumatic Diseases Using Administrative Health Databases: A Systematic Review. (Abstract)

Defining Depression and Anxiety in Individuals With Rheumatic Diseases Using Administrative Health Databases: A Systematic Review. To conduct a systematic review to describe how administrative health databases have been used to study depression and anxiety in patients with rheumatic diseases and to synthesize the case definitions that have been applied.Search strategies to identify articles evaluating depression and anxiety among individuals with rheumatic diseases were employed in Medline (...) , Embase, CINAHL, Cochrane Database of Systematic Reviews, and PsycINFO. Studies included were those using administrative health data and reporting case definitions for depression and anxiety using International Classification of Diseases (ICD) codes. We extracted information on study design and objectives, administrative health database, specific data sources (e.g., inpatient, pharmacy records), ICD codes, operational definitions, and validity of case definitions.Of the 36 studies included

2020 Arthritis care & research

16. Effect of peer support on patient anxiety during the coronary angiography or percutaneous coronary intervention perioperative period: a protocol for a systematic review and meta-analysis of randomised controlled trials. (Full text)

Effect of peer support on patient anxiety during the coronary angiography or percutaneous coronary intervention perioperative period: a protocol for a systematic review and meta-analysis of randomised controlled trials. The purpose of this study is to investigate the effect of peer support on patient anxiety during the perioperative period of coronary angiography or percutaneous coronary intervention (PCI).We will search the following databases (PubMed, Web of Science, EMBASE, Cochrane Library (...) index. Additionally, the Grading of Recommendations Assessment, Development and Evaluation system will be used to assess the quality of evidence.No ethics approval will be required since this is a systematic review of published studies. We aim to report information regarding the effects of peer support on patient anxiety during the perioperative period of coronary angiography or PCI. This systematic review and meta-analysis will be submitted to a peer-reviewed journal for publication.CRD42019123290

2020 BMJ open PubMed abstract

17. Reply to Bao et al.: Comment on sleep in the anxiety-related disorders: A meta-analysis of subjective and objective research. (Abstract)

Reply to Bao et al.: Comment on sleep in the anxiety-related disorders: A meta-analysis of subjective and objective research. 32330836 2020 04 24 1532-2955 52 2020 Apr 04 Sleep medicine reviews Sleep Med Rev Reply to Bao et al.: Comment on sleep in the anxiety-related disorders: A meta-analysis of subjective and objective research. 101315 S1087-0792(20)30058-7 10.1016/j.smrv.2020.101315 Cox Rebecca C RC Vanderbilt University, Department of Psychology, 301 Wilson Hall, 111 21st Ave South

2020 Sleep medicine reviews

18. What are the optimal measures to identify anxiety and depression in people diagnosed with head and neck cancer (HNC): a systematic review. (Full text)

What are the optimal measures to identify anxiety and depression in people diagnosed with head and neck cancer (HNC): a systematic review. A cancer diagnosis is potentially life-threatening, likely causing distress and uncertainty, which may be psychologically debilitating. Depression and anxiety are commonly underdiagnosed and undertreated in cancer patients. Head and neck cancer (HNC) patients face particular challenges that may contribute to distress. This review aims to: i) identify patient (...) reported outcome measures (PROMs) designed to assess anxiety and depression in HNC; and ii) determine their suitability for use in research and clinical practice to screen patients.We searched five electronic databases between July 2007 to July 2019 for studies assessing anxiety and depression in HNC patients. Searches were limited to this period to account for advances in cancer treatment. Records were screened for eligibility by one reviewer and 10% cross-checked by a second across all stages

2020 Journal of Patient-Reported Outcomes PubMed abstract

19. Nonpharmacological Interventions for Anxiety and Dementia in Nursing Homes: A Systematic Review. (Full text)

Nonpharmacological Interventions for Anxiety and Dementia in Nursing Homes: A Systematic Review. Anxiety is a major mental disorder in later life that impacts on activities of daily living and quality of life for adults living with dementia in nursing homes. The aim of this article was to systematically review nonpharmacological interventions for older adults living in nursing homes who experience comorbid anxiety and dementia.A systematic literature search was conducted across key databases (...) (Cinahl, ASSIA, Cochrane reviews and trials, psycARTICLES, psycINFO, and PubMed) to identify studies measuring anxiety as an outcome for an intervention for older adults living with dementia in nursing homes, up to December 31, 2017.The search yielded a total of 1,925 articles with 45 articles accessed for full article review. A total of 13 articles were included in this review following quality appraisal based on Cochrane methodology with six different anxiety measures used. The studies included were

2020 The Gerontologist PubMed abstract

20. The prevalence of anxiety symptoms in infertile women: a systematic review and meta-analysis. (Full text)

The prevalence of anxiety symptoms in infertile women: a systematic review and meta-analysis. Infertile women are exposed more frequently to anxiety risk than are infertile men, thereby adversely affecting the procedures with which they are treated and the quality of their lives. Yet, this problem is often disregarded. This study accordingly determined the prevalence of anxiety symptoms among infertile women.All Persian and English studies published from the early 2000s to May 2019 were (...) of the studies was assessed using the I2 statistic, and indicators of publication bias were ascertained using Egger's test. Stata (version 14) was employed in analyzing the findings.Thirteen studies having a collective sample size of 5055 infertile women were subjected to meta-analysis, with study heterogeneity incorporated into a random effects model. The findings indicated that 36% of the infertile women involved in the evaluated studies self-reported their experience with anxiety. The pooled prevalence

2020 Fertility research and practice PubMed abstract