Latest & greatest articles for asthma

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on asthma or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on asthma and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for asthma

21. Effect of Avoiding Cow's Milk Formula at Birth on Prevention of Asthma or Recurrent Wheeze Among Young Children: Extended Follow-up From the ABC Randomized Clinical Trial Full Text available with Trip Pro

Effect of Avoiding Cow's Milk Formula at Birth on Prevention of Asthma or Recurrent Wheeze Among Young Children: Extended Follow-up From the ABC Randomized Clinical Trial Effect of Avoiding Cow's Milk Formula at Birth on Prevention of Asthma or Recurrent Wheeze Among Young Children: Extended Follow-up From the ABC Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History (...) navigation JAMA Netw Open Actions . 2020 Oct 1;3(10):e2018534. doi: 10.1001/jamanetworkopen.2020.18534. Effect of Avoiding Cow's Milk Formula at Birth on Prevention of Asthma or Recurrent Wheeze Among Young Children: Extended Follow-up From the ABC Randomized Clinical Trial , , , , , , , Affiliations Expand Affiliations 1 Division of Molecular Epidemiology, Jikei University School of Medicine, Tokyo, Japan. 2 Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan. PMID: 33006618

2020 EvidenceUpdates

22. Asthma – optimising long-term management with inhaled corticosteroid

Asthma – optimising long-term management with inhaled corticosteroid ACE Clinical Guidances (ACGs) ACE Clinical Guidances (ACGs) ACE Clinical Guidances (ACGs) [also known as Appropriate Care Guides] ACGs provide concise, evidence-based recommendations to inform specific areas of clinical practice, and serve as a common starting point nationally for clinical decision-making. ACGs are underpinned by a wide array of considerations contextualised to Singapore, based on best available evidence (...) at the time of development. Each ACG is developed in collaboration with a multidisciplinary group of local experts representing relevant specialties and practice settings. ACGs are not exhaustive of the subject matter and do not replace clinical judgement. Published on 15 Oct 2020 Last Updated on 15 Oct 2020 This ACE Clinical Guidance (ACG) covers clinical assessment, pharmacological treatment, and non-pharmacological strategies for managing asthma over the long term, with a focus on inhaled

2020 Publication 4896151

23. The association between COVID-19 and asthma: a systematic review and meta-analysis Full Text available with Trip Pro

The association between COVID-19 and asthma: a systematic review and meta-analysis The association between COVID‐19 and asthma: A systematic review and meta‐analysis - Wang - 2020 - Clinical & Experimental Allergy - Wiley Online Library Working off-campus? Learn about our By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term RESEARCH LETTER Free Access The association between COVID‐19 and asthma: A systematic review (...) September 2020 Citations: Yushu Wang and Guangyu Ao contributed equally to this work. Give access Share full-text access Please review our and check box below to share full-text version of article. I have read and accept the Wiley Online Library Terms and Conditions of Use Shareable Link Use the link below to share a full-text version of this article with your friends and colleagues. Copy URL Share a link Share on However, there is no clear evidence about whether patients with asthma were at a higher

2020 Clinical & Experimental Allergy

24. Primary prevention of asthma: from risk and protective factors to targeted strategies for prevention. Full Text available with Trip Pro

Primary prevention of asthma: from risk and protective factors to targeted strategies for prevention. Asthma is a complex disease that often starts in childhood. Genomic and environmental factors as well as aberrant immune maturation early in life can contribute to the onset of disease, with great disparity over time and geographical regions. Epidemiological studies have scrutinised environmental exposures and attempted to translate these exposures into prevention strategies. Some approaches (...) for patients with asthma have been successful (eg, smoking ban, the Finnish Asthma Programme), and primary prevention of wheeze in pre-school children (age 0-5 years) by the supplementation of vitamin D or fish oil, or both, to pregnant women seems promising. Several recent prevention initiatives are based on strong asthma-protective environmental microbial exposures associated with traditional rural lifestyles. Preclinical studies with various bacterial lysates, bacterial and dietary metabolites

2020 Lancet

25. Sublingual immunotherapy for asthma. (Abstract)

Sublingual immunotherapy for asthma. Asthma is a common long-term respiratory disease affecting approximately 300 million people worldwide. Approximately half of people with asthma have an important allergic component to their disease, which may provide an opportunity for targeted treatment. Sublingual immunotherapy (SLIT) aims to reduce asthma symptoms by delivering increasing doses of an allergen (e.g. house dust mite, pollen extract) under the tongue to induce immune tolerance. Fifty-two (...) articles found trials up to 25 March 2015. The most recent search for trials for the current update was conducted on 29 October 2019.We included parallel randomised controlled trials, irrespective of blinding or duration, that evaluated sublingual immunotherapy versus placebo or as an add-on to standard asthma management. We included both adults and children with asthma of any severity and with any allergen-sensitisation pattern. We included studies that recruited participants with asthma, rhinitis

2020 Cochrane

26. Effectiveness and safety of three different traditional Chinese therapies for asthma in minors:A systematic review and network meta-analysis protocol Full Text available with Trip Pro

Effectiveness and safety of three different traditional Chinese therapies for asthma in minors:A systematic review and network meta-analysis protocol Inplasy Protocol 780 - INPLASY.COM International Platform of Registered Systematic Review and Meta-analysis Protocols Main Menu Share this: Copyright © 2021 INPLASY.COM Powered by INPLASY.COM

2020 INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols

27. Interleukin-4 gene polymorphism (C33T) and the risk of the asthma: A meta-analysis based on 24 studies Full Text available with Trip Pro

Interleukin-4 gene polymorphism (C33T) and the risk of the asthma: A meta-analysis based on 24 studies Interleukin-4 gene polymorphism (C33T) and the risk of the asthma: A meta-analysis based on 24 studies | Research Square Browse Tools & Services Your Cart See the published version of this article at . This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting (...) of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice. Research article Interleukin-4 gene polymorphism (C33T) and the risk of the asthma: A meta-analysis based on 24 studies Danyal Imani, Mohammad Masoud Eslami, Gholamreza Anani Sarab, Mansur Aliyu, Bahman Razi, Ramazan rezaei Danyal Imani Tehran University of Medical Sciences Mohammad Masoud Eslami Tarbiat Modares University

2020 Research Square

28. Does Prenatal Anxiety or Depression Symptoms Associate With Asthma or Atopic Diseases Throughout the Offspring's Childhood? An Updated Systematic Review and Meta-analysis Full Text available with Trip Pro

Does Prenatal Anxiety or Depression Symptoms Associate With Asthma or Atopic Diseases Throughout the Offspring's Childhood? An Updated Systematic Review and Meta-analysis Does Prenatal Anxiety or Depression Symptoms Associate With Asthma or Atopic Diseases Throughout the Offspring's Childhood? An Updated Systematic Review and Meta-analysis | Research Square Browse Tools & Services Your Cart This preprint is under consideration at BMC Pregnancy and Childbirth . A preprint is a preliminary (...) version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice. Research article Does Prenatal Anxiety or Depression Symptoms Associate With Asthma or Atopic Diseases Throughout the Offspring's Childhood? An Updated Systematic

2020 Research Square

29. Effect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D Levels: The VDKA Randomized Clinical Trial. (Abstract)

Effect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D Levels: The VDKA Randomized Clinical Trial. Severe asthma exacerbations cause significant morbidity and costs. Whether vitamin D3 supplementation reduces severe childhood asthma exacerbations is unclear.To determine whether vitamin D3 supplementation improves the time to a severe exacerbation in children with asthma and low vitamin D levels.The Vitamin D to Prevent Severe Asthma (...) Exacerbations (VDKA) Study was a randomized, double-blind, placebo-controlled clinical trial of vitamin D3 supplementation to improve the time to severe exacerbations in high-risk children with asthma aged 6 to 16 years taking low-dose inhaled corticosteroids and with serum 25-hydroxyvitamin D levels less than 30 ng/mL. Participants were recruited from 7 US centers. Enrollment started in February 2016, with a goal of 400 participants; the trial was terminated early (March 2019) due to futility, and follow

2020 JAMA

30. Air pollution and family related determinants of asthma onset and persistent wheezing in children: nationwide case-control study. Full Text available with Trip Pro

Air pollution and family related determinants of asthma onset and persistent wheezing in children: nationwide case-control study. To identify risk factors (air pollution and family related) for the onset of asthma and persistent wheezing in children.Nationwide case-control study.Denmark.All Danish children born from 1997 to 2014 and followed for asthma onset and persistent wheezing from age 1 year to 15 years.Onset of asthma and persistent wheezing.A higher incidence of asthma was found (...) in children of parents with asthma (adjusted hazard ratio 2.29 (95% confidence interval 2.22 to 2.35) and mothers who smoked during pregnancy (1.20, 1.18 to 1.22), whereas a lower incidence was found in children of parents with high educational attainment (0.72, 0.69 to 0.75) and high incomes (0.85, 0.81 to 0.89). Exposure to particulate matter ≤2.5 µm (PM2.5) and ≤10 µm (PM10) and nitrate was associated with an increased risk of asthma and persistent wheezing, with hazard ratios per 5 µg/m3 increase

2020 BMJ

31. Self-management interventions to reduce healthcare use and improve quality of life among patients with asthma: systematic review and network meta-analysis. Full Text available with Trip Pro

Self-management interventions to reduce healthcare use and improve quality of life among patients with asthma: systematic review and network meta-analysis. To compare the different self-management models (multidisciplinary case management, regularly supported self-management, and minimally supported self-management) and self-monitoring models against usual care and education to determine which are most effective at reducing healthcare use and improving quality of life in asthma.Systematic (...) review and network meta-analysis.Medline, the Cochrane Library, CINAHL, EconLit, Embase, Health Economics Evaluations Database, NHS Economic Evaluation Database, PsycINFO, and ClinicalTrials.gov from January 2000 to April 2019.Randomised controlled trials involving the different self-management models for asthma were included. The primary outcomes were healthcare use (hospital admission or emergency visit) and quality of life. Summary standardised mean differences (SMDs) and 95% credible intervals

2020 BMJ

32. Respiratory syncytial virus prophylaxis for prevention of recurrent childhood wheeze and asthma: a systematic review Full Text available with Trip Pro

Respiratory syncytial virus prophylaxis for prevention of recurrent childhood wheeze and asthma: a systematic review Respiratory syncytial virus prophylaxis for prevention of recurrent childhood wheeze and asthma: a systematic review | Research Square Browse Tools & Services Your Cart See the published version of this article at . This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior (...) to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice. Research Respiratory syncytial virus prophylaxis for prevention of recurrent childhood wheeze and asthma: a systematic review Lauren Quinn, Michael D Shields, Ian Sinha, Helen E Groves Lauren Quinn Queen's University Belfast School of Medicine Dentistry and Biomedical Sciences Corresponding

2020 Research Square

33. Asthma and COVID-19 - A systematic review Full Text available with Trip Pro

Asthma and COVID-19 - A systematic review Asthma and COVID-19 - A systematic review | Research Square Browse Tools & Services Your Cart See the published version of this article at . This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination (...) as established information or for guiding clinical practice. Short report Asthma and COVID-19 - A systematic review Natália F. Mendes, Carlos P. Jara, Eli Mansour, Eliana P. Araújo, Licio Velloso Natália F. Mendes Universidade Estadual de Campinas Carlos P. Jara Universidade Estadual de Campinas Eli Mansour Universidade Estadual de Campinas Eliana P. Araújo Universidade Estadual de Campinas Licio Velloso Universidade Estadual de Campinas Corresponding Author ORCiD: https://orcid.org/0000-0002-4806-7218 DOI

2020 Research Square

34. Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews. Full Text available with Trip Pro

Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews. Asthma is an illness that commonly affects adults and children, and it serves as a common reason for children to attend emergency departments. An asthma exacerbation is characterised by acute or subacute worsening of shortness of breath, cough, wheezing, and chest tightness and may be triggered by viral respiratory infection, poor compliance with usual medication, a change (...) in the weather, or exposure to allergens or irritants. Most children with asthma have mild or moderate exacerbations and respond well to first-line therapy (inhaled short-acting beta-agonists and systemic corticosteroids). However, the best treatment for the small proportion of seriously ill children who do not respond to first-line therapy is not well understood. Currently, a large number of treatment options are available and there is wide variation in management.Main objective - To summarise Cochrane

2020 Cochrane

35. Management of Severe Asthma

Management of Severe Asthma Management of Severe Asthma: a European Respiratory Society/American Thoracic Society Guideline | European Respiratory Society Main menu User menu Search Search for this keyword Search for this keyword Management of Severe Asthma: a European Respiratory Society/American Thoracic Society Guideline Fernando Holguin , Juan Carlos Cardet , Kian Fan Chung , Sarah Diver , Diogenes S. Ferreira , Anne Fitzpatrick , Mina Gaga , Liz Kellermeyer , Sandhya Khurana , Shandra (...) Parana, Curitiba, Brazil 6 School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia Anne Fitzpatrick 7 Emory University, Division of Pulmonology Allergy/Immunology, Cystic Fibrosis and Sleep, Atlanta, GA, USA Mina Gaga 8 Athens Chest Hospital, Respiratory Medicine Department and Asthma Centre, Athens, Greece Liz Kellermeyer 9 Biomedical Library, National Jewish Health, Denver, CO, USA Sandhya Khurana 10 Pulmonary Diseases and Critical Care, University of Rochester

2020 American Thoracic Society

36. Managing Chronic Cough Due to Asthma and NAEB in Adults and Adolescents: CHEST Guideline and Expert Panel Report Full Text available with Trip Pro

: Asthma and non-asthmatic eosinophilic bronchitis (NAEB) are among the commonest causes of chronic cough in adults. We sought to determine the role of non-invasive measurements of airway inflammation, including induced sputum and fractional exhaled nitric oxide, in the evaluation of cough associated with asthma, and what the best treatment is for cough due to asthma or NAEB. Methods: We undertook three systematic reviews of randomized controlled trials and observational trials of adults (...) Managing Chronic Cough Due to Asthma and NAEB in Adults and Adolescents: CHEST Guideline and Expert Panel Report Managing Chronic Cough Due to Asthma and NAEB in Adults and Adolescents: CHEST Guideline and Expert Panel Report - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get

2020 EvidenceUpdates

37. Combination of ipratropium bromide and salbutamol in children and adolescents with asthma: a meta-analysis Full Text available with Trip Pro

Combination of ipratropium bromide and salbutamol in children and adolescents with asthma: a meta-analysis Combination of ipratropium bromide and salbutamol in children and adolescents with asthma: a meta-analysis | bioRxiv Search for this keyword Confirmatory Results Combination of ipratropium bromide and salbutamol in children and adolescents with asthma: a meta-analysis Hongzhen Xu , Lin Tong , Peng Gao , Yan Hu , Huijuan Wang , Zhimin Chen , Luo Fang doi: https://doi.org/10.1101 (...) School of Medicine, National Clinical Research Center for Child Health , Hangzhou, Zhejiang, China For correspondence: Luo Fang b .Department of Pharmacy, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health , Hangzhou, Zhejiang, China For correspondence: Abstract Background A combination of ipratropium bromide (IB) and salbutamol is commonly used to treat asthma in children and adolescents; however, there has been a lack of consistency

2020 Cold Spring Harbor Laboratory

38. Review for "Preschool wheezing and asthma in children: a systematic review of guidelines and quality appraisal with the Agree II Instrument" Full Text available with Trip Pro

Review for "Preschool wheezing and asthma in children: a systematic review of guidelines and quality appraisal with the Agree II Instrument" Preschool wheezing and asthma in children: A systematic review of guidelines and quality appraisal with the AGREE II instrument | Publons  Preschool wheezing and asthma in children: A systematic review of guidelines and quality appraisal with the AGREE II instrument Review badges  5 pre-pub reviews  0 post-pub reviews Identifiers Navigate in Preschool (...) wheezing and asthma in children: A systematic review of guidelines and quality appraisal with the AGREE II instrument Published in Web of Science (Free Access) Abstract Authors Ruszczynski, Marek; Ambrozej, Dominika; Adamiec, Aleksander; Ryczaj, Klaudia; Elenius, Varpu; Cavkaytar, Ozlem; Maggina, Paraskevi; Makrinioti, Heidi; Papadopoulos, Nikolaos; Hedlin, Gunilla; Konradsen, Jon R.; Schaub, Bianca; H. Smits, Hermelijn; Jartti, Tuomas; Feleszko, Wojciech Publons users who've claimed - Contributors

2020 Wiley

39. The Therapeutic Effect of Extracellular Vesicles on Asthma in Pre-clinical Models: A Systematic Review Protocol Full Text available with Trip Pro

to respiratory distress and even death. A number of medications are available and prescribed to manage asthma. Yet despite that, only half of the asthmatic patients are able to control their condition. Extracellular vesicles (EVs) play an important role in transporting contents such as nucleic acids, proteins, and lipids to other cells. While EVs have been extensively studied as biomarkers of various pathological states, evidence indicates that they can play protective and therapeutic roles in mitigating (...) The Therapeutic Effect of Extracellular Vesicles on Asthma in Pre-clinical Models: A Systematic Review Protocol The Therapeutic Effect of Extracellular Vesicles on Asthma in Pre-clinical Models: A Systematic Review Protocol[v1] | Preprints Share this article with Create alert Email: Submit > > > doi: 10.20944/preprints202007.0349.v1 Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed The Therapeutic Effect of Extracellular Vesicles on Asthma in Pre-clinical Models

2020 MDPI AG

40. Statins for asthma. (Abstract)

Statins for asthma. Asthma is a common chronic respiratory disease. People with asthma have inflammation of their airways that causes recurrent episodes of wheezing, breathlessness and chest tightness, with or without a cough. Statins possess multiple therapeutic effects, including lowering lipid levels in the blood. Statins are reported to have a potential role as an adjunct treatment in asthma. However, comprehensive evidence of the benefits and harms of using statins is required (...) to facilitate decision making.To assess the benefits and harms of statins as an adjunct therapy for asthma in adults and children.We searched for studies in the Cochrane Airways Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE Ovid SP and Embase Ovid SP, from their inception dates We handsearched the proceedings of major respiratory conferences. We also searched clinical trials registries for completed, ongoing and unpublished studies, and scanned the reference lists

2020 Cochrane