Latest & greatest articles for fatigue

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Top results for fatigue

21. The Effects of the COMMASH-E Intervention on the Fatigue, Sleep Quality and Functional Status of Children with Cancer in Indonesia. (Abstract)

The Effects of the COMMASH-E Intervention on the Fatigue, Sleep Quality and Functional Status of Children with Cancer in Indonesia. This study aimed to investigate the effects of the combined music and sleep hygiene education (COMMASH-E) intervention on the fatigue, sleep quality and functional status of children with cancer residing in temporary lodges in Indonesia. The design of this study was a quasi-experimental pre-post test with a control group. We recruited children with cancer aged 7-18 (...)  years (n = 58) using a consecutive sampling method and assigned them to intervention and control groups (n = 29 in each group). The intervention group had the COMMASH-E intervention while the control group received routine care. Fatigue, sleep quality and functional status were measured on days 1 and 4 using Allen's Fatigue in Childhood Cancer Scale, the Sleep Problem in Children Scale and the Barthel Index, respectively. T-dependent and independent tests and Multivariate Analysis of Covariance

2019 Comprehensive child and adolescent nursing Controlled trial quality: uncertain

22. Relative Impact of Pain and Fatigue on Work Productivity in Patients with Rheumatoid Arthritis from the RA-BEAM Baricitinib Trial. Full Text available with Trip Pro

Relative Impact of Pain and Fatigue on Work Productivity in Patients with Rheumatoid Arthritis from the RA-BEAM Baricitinib Trial. To explore the relationship of pain and fatigue with daily activity and work productivity in rheumatoid arthritis (RA) patients from the baricitinib clinical trial, RA-BEAM.In RA-BEAM, a double-blind phase 3 study, patients were randomized 3:3:2 to placebo (n = 488), baricitinib 4 mg once daily (n = 487), or adalimumab 40 mg biweekly (n = 330) with background (...) methotrexate. The Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) measured fatigue and the pain visual analog scale (0-100 mm) assessed pain. Work Productivity and Activity Impairment Questionnaire-RA measured daily activity and work productivity. At weeks 12 and 24, pain was assessed using pain reduction (< 30%, 30% to < 50%, ≥ 50%) and overall pain score; clinically relevant FACIT-F changes were assessed by values < 3.56 and ≥ 3.56 and the FACIT-F normative value score (< 40.1, ≥ 40.1

2019 Rheumatology and therapy Controlled trial quality: uncertain

23. The impact of fatigue in the healthcare setting

health and safety outcomes ? fewer workplace incidents and injuries ? reductions in absenteeism and staff turnover, and ? better performance and productivity. Fatigue is a product of workload and a cause for burnout – thus ultimately affecting recruitment and retention of physicians both in community and acute care settings [1]. Collective actions at the organisational level that promote clinicians abilities to rest sufficiently after work and prevent them from becoming tired or exhausted (...) and workload Context Healthcare setting only Types of information Peer reviewed literature, grey literature Timeframe 2014 - current Results Definition of fatigue Fatigue is a complex phenomenon that can be attributed to many factors and difficult to find a comprehensive definition [3]. Fatigue usually refers to impairment in task performance at an individual’s normal capacity. A state of feeling tired, weary, or sleepy that results from prolonged mental and physical workload, extended periods of anxiety

2019 Monash Health Evidence Reviews

24. Lived experiences of patients on hemodialytic treatment: A discursive perspective on fatigue and motivational issues Full Text available with Trip Pro

Lived experiences of patients on hemodialytic treatment: A discursive perspective on fatigue and motivational issues Fatigue is an incapacitating symptom for patients on chronic hemodialysis treatment. This study explored the relationship between hemodialysis patients' subjective experience and motivation. The investigation of patients' narratives and fatigue-related factors was performed by holding semi-structured interviews with 31 hemodialysis patients. Fatigue Severity Scale and Behavioral (...) Inhibition/Activation System questionnaire were used to assess fatigue severity and motivational mechanisms. Results showed significant differences in the use of specific topics and words (such as "family," "to manage," "dialysis," "psychological issues") depending on high, medium, and low Behavioral Inhibition System, Behavioral Activation System, and Fatigue Severity Scale scores, indicating that hemodialysis patients' narratives contain keywords related to the motivational sphere.

2018 Health psychology open

25. WITHDRAWN: Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome. Full Text available with Trip Pro

WITHDRAWN: Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome. Chronic fatigue is increasingly common. Conventional medical care is limited in treating chronic fatigue, leading some patients to use traditional Chinese medicine therapies, including herbal medicine.To assess the effectiveness of traditional Chinese medicine herbal products in treating idiopathic chronic fatigue and chronic fatigue syndrome.The following databases were (...) searched for terms related to traditional Chinese medicine, chronic fatigue, and clinical trials: CCDAN Controlled Trials Register (July 2009), MEDLINE (1966-2008), EMBASE (1980-2008), AMED (1985-2008), CINAHL (1982-2008), PSYCHINFO (1985-2008), CENTRAL (Issue 2 2008), the Chalmers Research Group PedCAM Database (2004), VIP Information (1989-2008), CNKI (1976-2008), OCLC Proceedings First (1992-2008), Conference Papers Index (1982-2008), and Dissertation Abstracts (1980-2008). Reference lists

2018 Cochrane

26. Graded exercise therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective and unsafe. Re-analysis of a Cochrane review Full Text available with Trip Pro

Graded exercise therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective and unsafe. Re-analysis of a Cochrane review The analysis of the 2017 Cochrane review reveals flaws, which means that contrary to its findings, there is no evidence that graded exercise therapy is effective. Because of the failure to report harms adequately in the trials covered by the review, it cannot be said that graded exercise therapy is safe. The analysis of the objective outcomes in the trials (...) provides sufficient evidence to conclude that graded exercise therapy is an ineffective treatment for myalgic encephalomyelitis/chronic fatigue syndrome.

2018 Health psychology open

27. Dead tired: evaluating the physiological status and survival of neonatal reef sharks under stress Full Text available with Trip Pro

Dead tired: evaluating the physiological status and survival of neonatal reef sharks under stress Marine protected areas (MPAs) can protect shark populations from targeted fisheries, but resident shark populations may remain exposed to stressors like capture as bycatch and environmental change. Populations of young sharks that rely on shallow coastal habitats, e.g. as nursery areas, may be at risk of experiencing these stressors. The purpose of this study was to characterize various components (...) of the physiological stress response of neonatal reef sharks following exposure to an exhaustive challenge under relevant environmental conditions. To accomplish this, we monitored markers of the secondary stress response and measured oxygen uptake rates ( M˙O2 ) to compare to laboratory-derived baseline values in neonatal blacktip reef (Carcharhinus melanopterus) and sicklefin lemon sharks (Negaprion acutidens). Measurements occurred over three hours following exposure to an exhaustive challenge (gill-net capture

2018 Conservation physiology

28. Chronic fatigue syndrome/Myalgic encephalomyelitis

-exertional malaise (PEM)/exertional exhaustion, unrefreshing sleep, cognitive and autonomic dysfunction, myalgia, arthralgia, headaches, and sore throat and tender lymph nodes (without palpable lymphadenopathy), with symptoms lasting at least 6 months. Komaroff AL. Myalgic encephalomyelitis/chronic fatigue syndrome: a real illness. Ann Intern Med. 2015 Jun 16;162(12):871-2. http://annals.org/article.aspx?articleid=2322808 http://www.ncbi.nlm.nih.gov/pubmed/26075760?tool=bestpractice.com The fatigue (...) =bestpractice.com to PEM/exertional exhaustion in ME/CFS as defined by the Canadian Consensus Criteria, Carruthers BM, Jain AK, De Meirleir KL, et al. Myalgic encephalomyelitis/chronic fatigue syndrome: clinical working case definition, diagnostic and treatment protocols. 2003 [internet publication]. http://med.stanford.edu/content/dam/sm/chronicfatigue/documents/overview/CanadianCriteriaCFS2003.pdf Jason LA, Evans M, Porter N, et al. The development of a revised Canadian myalgic encephalomyelitis chronic

2018 BMJ Best Practice

29. Cognitive behavioural therapy with optional graded exercise therapy in patients with severe fatigue with myotonic dystrophy type 1: a multicentre, single-blind, randomised trial Full Text available with Trip Pro

Cognitive behavioural therapy with optional graded exercise therapy in patients with severe fatigue with myotonic dystrophy type 1: a multicentre, single-blind, randomised trial Myotonic dystrophy type 1 is the most common form of muscular dystrophy in adults and leads to severe fatigue, substantial physical functional impairment, and restricted social participation. In this study, we aimed to determine whether cognitive behavioural therapy optionally combined with graded exercise compared (...) with standard care alone improved the health status of patients with myotonic dystrophy type 1.We did a multicentre, single-blind, randomised trial, at four neuromuscular referral centres with experience in treating patients with myotonic dystrophy type 1 located in Paris (France), Munich (Germany), Nijmegen (Netherlands), and Newcastle (UK). Eligible participants were patients aged 18 years and older with a confirmed genetic diagnosis of myotonic dystrophy type 1, who were severely fatigued (ie, a score

2018 EvidenceUpdates

30. Multidisciplinary rehabilitation treatment is not effective for myalgic encephalomyelitis/chronic fatigue syndrome: A review of the FatiGo trial Full Text available with Trip Pro

Multidisciplinary rehabilitation treatment is not effective for myalgic encephalomyelitis/chronic fatigue syndrome: A review of the FatiGo trial The FatiGo trial concluded that multidisciplinary rehabilitation treatment is more effective for chronic fatigue syndrome/myalgic encephalomyelitis in the long term than cognitive behaviour therapy and that multidisciplinary rehabilitation treatment is more cost-effective for fatigue and cognitive behaviour therapy for quality of life. However, FatiGo (...) suffered from a number of serious methodological flaws. Moreover, it ignored the results of the activity metre, its only objective outcome. This jeopardizes the validity of FatiGo. Its analysis shows that there was no statistically significant difference between multidisciplinary rehabilitation treatment and cognitive behaviour therapy and neither are (cost-)effective. FatiGo's claims of efficacy of multidisciplinary rehabilitation treatment and cognitive behaviour therapy for chronic fatigue syndrome

2018 Health psychology open

31. Impact of abiraterone acetate plus prednisone or enzalutamide on fatigue and cognition in patients with metastatic castration-resistant prostate cancer: initial results from the observational AQUARiUS study Full Text available with Trip Pro

Impact of abiraterone acetate plus prednisone or enzalutamide on fatigue and cognition in patients with metastatic castration-resistant prostate cancer: initial results from the observational AQUARiUS study Abiraterone acetate plus prednisone (AAP) and enzalutamide (ENZ) are commonly prescribed for metastatic castration-resistant prostate cancer (mCRPC). Data comparing their effects on patient-reported outcomes (PROs) from routine clinical practice are limited.AQUARiUS (NCT02813408 (...) ) is an ongoing, two-cohort, prospective, observational, non-randomised, multicentre, phase IV European study assessing the effects of AAP and ENZ on PROs in 211 patients with mCRPC over 12 months. Patients receive AAP or ENZ per routine clinical practice. Data on cognition, fatigue, pain and health-related quality of life are measured using the Functional Assessment of Cancer Therapy-Cognitive Function, Brief Fatigue Inventory-Short Form, Brief Pain Inventory-Short Form and European Organization for Research

2018 ESMO open

32. Fatigue

questions please contact us via jon.brassey@tripdatabase.com Top results for fatigue 1. Tiredness / fatigue in adults Tiredness / fatigue in adults - NICE CKS Clinical Knowledge Summaries Share Tiredness / fatigue in adults - Summary Tiredness (or fatigue ) is often described as a lack of, or decreased, energy, and physical or mental exhaustion . Tiredness may be due to psychological, psychosocial, physical, or physiological causes or a combination of these. Between 10–18% of people in the UK report (...) there are no curative treatments. Among people with ALS/MND, fatigue is a common and debilitating symptom, which is characterised by reversible motor weakness and whole-body tiredness that is only partially relieved by rest. The effectiveness of pharmacological or non (...) -pharmacological treatments for fatigue in ALS/MND is not yet established. OBJECTIVES: To assess the effects of pharmacological and non-pharmacological interventions for fatigue in ALS/MND. SEARCH METHODS: We searched the following databases

2018 Trip Latest and Greatest

33. Occupational Exposure to Diesel and Gasoline Engine Exhausts and the Risk of Kidney Cancer in Canadian Men Full Text available with Trip Pro

Occupational Exposure to Diesel and Gasoline Engine Exhausts and the Risk of Kidney Cancer in Canadian Men Kidney cancer is the fifth most common incident cancer in Canadian men. Diesel and gasoline exhausts are common workplace exposures that have been examined as risk factors for non-lung cancer sites, including the kidney, but limitations in exposure assessment methods have contributed to inconsistent findings. The objective of this study was to assess the relationship between occupational (...) gasoline and diesel engine exhausts and the risk of kidney cancer in men.The National Enhanced Cancer Surveillance System (NECSS) is a Canadian population-based case-control study conducted in 1994-1997. Incident kidney cancer cases were identified using provincial registries, while the control series was identified through random-digit dialing, or provincial administrative databases. Self-reported questionnaires were used to obtain information on lifetime occupational history and cancer risk factors

2018 Annals of work exposures and health

34. Adventure-based training to promote physical activity and reduce fatigue among childhood cancer survivors: A randomized controlled trial (Abstract)

Adventure-based training to promote physical activity and reduce fatigue among childhood cancer survivors: A randomized controlled trial Cancer-related fatigue is one of the most distressing symptoms reported by childhood cancer survivors. Despite the body of evidence that regular physical activity helps alleviate cancer-related fatigue, insufficient participation in physical activity is frequently observed among childhood cancer survivors.This study examined the effectiveness of an adventure (...) -based training programme in promoting physical activity, reducing fatigue, and enhancing self-efficacy and quality of life among Hong Kong Chinese childhood cancer survivors.A prospective randomised controlled trial.A paediatric oncology outpatient clinic, a non-governmental organisation, and a non-profit voluntary organisation.Hong Kong Chinese childhood cancer survivors aged 9-16 years who reported symptoms of fatigue and had not engaged in regular physical exercise in the past 6 months.The

2018 EvidenceUpdates

35. Rituximab for the treatment of fatigue in primary biliary cholangitis (formerly primary biliary cirrhosis): a randomised controlled trial Full Text available with Trip Pro

Rituximab for the treatment of fatigue in primary biliary cholangitis (formerly primary biliary cirrhosis): a randomised controlled trial Rituximab for the treatment of fatigue in primary biliary cholangitis (formerly primary biliary cirrhosis): a randomised controlled trial Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation (...) or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} There was no difference in fatigue score in primary biliary cholangitis between Rituximab and a placebo at 3 months. {{author}} {{($index , , , , , , , , , , , & . Amardeep Khanna 1, 2, † , Laura Jopson 1, 2, † , Denise Howel 3 , Andrew Bryant 3 , Andrew Blamire 2 , Julia L Newton 2 , Jennifer Wilkinson 4 , Alison J Steel 4 , Jennifer

2018 NIHR HTA programme

36. Soluble interleukin-6 receptor mediated fatigue highlights immunological heterogeneity of patients with early breast cancer who undergo radiation therapy Full Text available with Trip Pro

Soluble interleukin-6 receptor mediated fatigue highlights immunological heterogeneity of patients with early breast cancer who undergo radiation therapy This study aimed to explore the associations between dose-volume parameters of localized breast irradiation, longitudinal interleukin-6 soluble receptor (sIL-6R), and leukocyte counts as markers of an immune-mediated response and fatigue as a centrally-driven behavior.This prospective cohort study recruited 100 women who were diagnosed (...) with stage 0-IIIa breast cancer, prescribed 40 Gy in 15 fractions over 3 weeks adjuvant radiation therapy, and had no prior or concurrent chemotherapy. Dose-volume parameters were derived from treatment plans and related to serum sIL-6R concentrations, leukocyte counts, and a validated measure of self-reported fatigue at baseline, after 10 and 15 fractions, and 4 weeks after radiation therapy.sIL-6R concertation was significantly higher in patients with a total volume of tissue irradiated within the 50

2018 Advances in radiation oncology

37. Randomised controlled trial of a self-guided online fatigue intervention in multiple sclerosis Full Text available with Trip Pro

Randomised controlled trial of a self-guided online fatigue intervention in multiple sclerosis Fatigue is a major disabling symptom in many chronic diseases including multiple sclerosis (MS), but treatment options are limited.Here, we tested the effectiveness of a self-guided , interactive, online fatigue management programme (ELEVIDA) based on principles of cognitive behavioural therapy (CBT) and related psychotherapeutic approaches (eg, mindfulness) for reducing fatigue in MS.Patients with MS (...) and self-reported fatigue were recruited via the website of the German MS Society and assigned via an automated randomisation generator (1:1, no blocking or stratification) to a 12-week online intervention (ELEVIDA, n=139, 82% female, mean age 40.8, median patient determined disease steps (PDDS) 3.0) or a waitlist control group (n=136, 79% female, mean age 41.9, median PDDS 3.0). The primary outcome was the Chalder Fatigue Scale. Outcomes were assessed at baseline, at week 12 (postintervention

2018 EvidenceUpdates

38. Fatigue and Patient Safety

Fatigue and Patient Safety Fatigue and Patient Safety - ACOG Menu ▼ Fatigue and Patient Safety Page Navigation ▼ Number 730, February 2018 (Replaces Committee Opinion No. 519, March 2012) Committee on Patient Safety and Quality Improvement This Committee Opinion was developed by the American College of Obstetricians and Gynecologists’ Committee on Patient Safety and Quality Improvement in collaboration with committee member Laurie C. Gregg, MD. This information is designed as an educational (...) , or otherwise, either express or implied. ACOG does not guarantee, warrant, or endorse the products or services of any firm, organization, or person. Neither ACOG nor its officers, directors, members, employees, or agents will be liable for any loss, damage, or claim with respect to any liabilities, including direct, special, indirect, or consequential damages, incurred in connection with this publication or reliance on the information presented. Fatigue and Patient Safety Abstract: Fatigue and sleep

2018 American College of Obstetricians and Gynecologists

39. Efficacy of web-based cognitive-behavioural therapy for chronic fatigue syndrome: randomised controlled trial Full Text available with Trip Pro

Efficacy of web-based cognitive-behavioural therapy for chronic fatigue syndrome: randomised controlled trial Face-to-face cognitive-behavioural therapy (CBT) leads to a reduction of fatigue in chronic fatigue syndrome (CFS). Aims To test the efficacy of internet-based CBT (iCBT) for adults with CFS.A total of 240 patients with CFS were randomised to either iCBT with protocol-driven therapist feedback or with therapist feedback on demand, or a waiting list. Primary outcome was fatigue severity (...) assessed with the Checklist Individual Strength (Netherlands Trial Register: NTR4013).Compared with a waiting list, intention-to-treat (ITT) analysis showed a significant reduction of fatigue for both iCBT conditions (protocol-driven feedback: B = -8.3, 97.5% CI -12.7 to -3.9, P < 0.0001; feedback on demand: B = -7.2, 97.5% CI -11.3 to -3.1, P < 0.0001). No significant differences were found between both iCBT conditions on all outcome measures (P = 0.3-0.9). An exploratory analysis revealed

2018 EvidenceUpdates

40. Multidimensional fatigue in pulmonary hypertension: prevalence, severity and predictors Full Text available with Trip Pro

Multidimensional fatigue in pulmonary hypertension: prevalence, severity and predictors Pulmonary hypertension is a potentially fatal disease. Despite pharmacological advances in pulmonary hypertension, fatigue remains common in patients with pulmonary hypertension. A convenience sample of 120 participants at an international patient conference completed the Multidimensional Fatigue Inventory (MFI)-20 scale. Data on New York Heart Association Functional Class, body mass index, oxygen use (...) and medication type/use were also collected. There was a high prevalence of "severe" to "very severe" fatigue for each dimension: General Fatigue (60%), Physical Fatigue (55.8%), Reduced Activity (41.7%), Reduced Motivation (32.5%) and Mental Fatigue (27.5%). The mean±sd overall MFI-20 score was 58±5.1. Dimensions with the highest averaged levels were General Fatigue (13.40±3.61), Physical Fatigue (13.23±3.67) and Reduced Activity (11.33±4.16). Body mass index correlated with higher fatigue scores

2018 ERJ open research