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Latest & greatest articles for hypertension
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on hypertension or other clinical topics then use Trip today.
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biopsy remains the reference standard for the assessment and diagnosis of cirrhosis, hepatic vein catheterization with measurement of the hepatic venous pressure gradient (HVPG) is currently the benchmark technique for determining portal pressure. The HVPG quantifies the degree of portal hypertension due to sinusoidal resistance to blood flow. The HVPG is calculated as the difference between the wedged hepatic venous pressure and the free hepatic venous pressure. A normal HVPG is between 1 and 5 mmHg (...) ; Bill S. Majdalany, MD c ; Charles Y. Kim, MD d ; Osmanuddin Ahmed, MD e ; Sumeet K. Asrani, MD, MSc f ; Brooks D. Cash, MD g ; Jens Eldrup-Jorgensen, MD h ; A. Tuba Kendi, MD i ; Matthew J. Scheidt, MD j ; David M. Sella, MD k ; Karin E. Dill, MD l ; Eric J. Hohenwalter, MD. m Summary of Literature Review Introduction/Background Portal hypertension is a common clinical syndrome, hemodynamically defined by a pathological increase of the portal pressure and by the formation of portal-systemic
Alcohol intake reduction for controlling hypertension. Highbloodpressure constitutes one of the leading causes of mortality and morbidity all over the world. At the same time, heavy drinking increases the risk for developing cardiovascular diseases, including cardiomyopathy, hypertension, atrial arrhythmias, or stroke. Several studies have already assessed specifically the relationship between alcohol intake and hypertension. However, the potential effect on bloodpressure of alcohol intake (...) reduction interventions is largely unknown.To assess the effect of any intervention to reduce alcohol intake in terms of bloodpressure decrease in hypertensive people with alcohol consumption compared to a control intervention or no intervention at all. To determine additional effects related to mortality, major cardiovascular events, serious adverse events, or quality of life.The Cochrane Hypertension Information Specialist searched the following databases for randomised controlled trials up to June
5 classes of antihypertensive drugs were not linked to positive COVID-19 test results or severe COVID-19. Reynolds HR, Adhikari S, Pulgarin C, et al. Renin-angiotensin-aldosterone system inhibitors and risk of Covid-19. N Engl J Med. 2020;382:2441-8. 32356628.
Bloodpressure targets for the treatment of people with hypertension and cardiovascular disease. This is the second update of the review first published in 2017. Hypertension is a prominent preventable cause of premature morbidity and mortality. People with hypertension and established cardiovascular disease are at particularly high risk, so reducing bloodpressure to below standard targets may be beneficial. This strategy could reduce cardiovascular mortality and morbidity but could also (...) 9484 participants. Mean follow-up was 3.7 years (range 1.0 to 4.7 years). All RCTs provided individual participant data. None of the included studies was blinded to participants or clinicians because of the need to titrate antihypertensives to reach a specific bloodpressure goal. However, an independent committee blinded to group allocation assessed clinical events in all trials. Hence, we assessed all trials at high risk of performance bias and low risk of detection bias. Other issues
Trends in BloodPressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018. Controlling bloodpressure (BP) reduces the risk for cardiovascular disease.To determine whether BP control among US adults with hypertension changed from 1999-2000 through 2017-2018.Serial cross-sectional analysis of National Health and Nutrition Examination Survey data, weighted to be representative of US adults, between 1999-2000 and 2017-2018 (10 cycles), including 18 262 US adults aged 18 years (...) or older with hypertension defined as systolic BP level of 140 mm Hg or higher, diastolic BP level of 90 mm Hg or higher, or use of antihypertensive medication. The date of final data collection was 2018.Calendar year.Mean BP was computed using 3 measurements. The primary outcome of BP control was defined as systolic BP level lower than 140 mm Hg and diastolic BP level lower than 90 mm Hg.Among the 51 761 participants included in this analysis, the mean (SD) age was 48 (19) years and 25 939 (50.1
Pharmacotherapy for hyperuricaemia in hypertensive patients. This is the second update of this systematic review. Highbloodpressure represents a major public health problem. Worldwide, approximately one-fourth of the adult population has hypertension. Epidemiological and experimental studies suggest a link between hyperuricaemia and hypertension. Hyperuricaemia affects 25% to 40% of those with untreated hypertension; a much lower prevalence has been reported in those with normotension (...) or in the general population. However, whether lowering serum uric acid (UA) might lower bloodpressure (BP), is an unanswered question.To determine whether UA-lowering agents reduce BP in people with primary hypertension or prehypertension, compared with placebo.The Cochrane Hypertension Information Specialist searched the following databases for randomised controlled trials up to May 2020: the Cochrane Hypertension Specialised Register, CENTRAL 2018, Issue 12, MEDLINE (from 1946), Embase (from 1974
hypertension refers to the untreated condition in which BP is elevated in the office but is normal when measured by ambulatory bloodpressure monitoring (ABPM), home bloodpressure measurement (HBPM), or both. Masked hypertension refers to untreated patients in whom the BP is normal in the office but is elevated when measured by HBPM or ABPM. Classification Based on the average BP recorded, hypertension is classified as High-Normal, Stage 1, Stage 2, or Stage 3 (Note: Figure 1 lists MOBP values only (...) device is recommended in patients with regular heart rate. [ Strong Recommendation, Strong Evidence ] Hypertension is diagnosed in adults when automated office bloodpressure reading is ≥ 135/85 in the higher BP arm. [ Strong Recommendation, Strong Evidence ] When a manual office bloodpressure device (MOBP) is used hypertension is diagnosed at ≥ 140/90. [ Strong Recommendation, Strong Evidence ] Consider 24-hour ambulatory bloodpressure monitoring, or standardized home bloodpressure monitoring
) system.This synopsis summarizes key features of the guideline in several key areas: the measurement of bloodpressure, the definition of hypertension, target treatment goals, and nonpharmacologic and pharmacologic treatment of essential and resistant hypertension. (...) Synopsis of the 2020 U.S. Department of Veterans Affairs/U.S. Department of Defense Clinical Practice Guideline: The Diagnosis and Management of Hypertension in the Primary Care Setting. In January 2020, the U.S. Department of Veterans Affairs (VA) and the U.S. Department of Defense (DoD) approved a joint clinical practice guideline for the diagnosis and management of hypertension in the primary care setting.The VA/DoD Evidence-Based Practice Work Group convened a joint VA/DoD guideline
Three-Year Outcomes of Bariatric Surgery in Patients With Obesity and Hypertension : A Randomized Clinical Trial. Midterm effects of bariatric surgery on patients with obesity and hypertension remain uncertain.To determine the 3-year effects of Roux-en-Y gastric bypass (RYGB) on bloodpressure (BP) compared with medical therapy (MT) alone.Randomized clinical trial. (ClinicalTrials.gov: NCT01784848).Investigator-initiated study at Heart Hospital (HCor), São Paulo, Brazil.Patients (...) with hypertension receiving at least 2 medications at maximum doses or more than 2 medications at moderate doses and with a body mass index (BMI) between 30.0 and 39.9 kg/m2 were randomly assigned (1:1 ratio).RYGB plus MT or MT alone.The primary outcome was at least a 30% reduction in total number of antihypertensive medications while maintaining BP less than 140/90 mm Hg. Key secondary outcomes were number of antihypertensive medications, hypertension remission, and BP control according to current guidelines
Thoracic Society clinical practice guideline update. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 2019; 3 : 177-198 Figure 1 An algorithm for the work-up of pulmonary hypertension (PH). ABG, arterial blood gas; CHD, congenital heart disease; CT, computed tomography; CTD, connective tissue disease; CTEPH, chronic thromboembolic pulmonary hypertension; DLCO, diffusion capacity of the lung for carbon monoxide; ECG, electrocardiogram; HR-CT, high-resolution computed tomography; mPAP (...) these modalities, particularly at high pulmonary artery pressure (PAP), and estimation of RA pressure according to inferior vena cava size and collapsibility is sometimes inaccurate. Fisher M.R. Forfia P.R. Chamera E. et al. Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med. 2009; 179 : 615-621 , Rich J.D. Shah S.J. Swamy R.S. Kamp A. Rich S. Inaccuracy of Doppler echocardiographic estimates of pulmonary artery pressures in patients
Diagnosis of hypertension using ambulatory bloodpressure monitoring in patients with clinic bloodpressure ? 140/90mmHg and ? 180/110mmHg 1 Public Summary Document Application No. 1572 – Diagnosis of hypertension using ambulatory bloodpressure monitoring in patients with clinic bloodpressure = 140/90mmHg and = 180/110mmHg Applicant: HighBloodPressure Research Council of Australia Inc. Date of MSAC consideration: MSAC 78 th Meeting, 3 April 2020 Context for decision: MSAC makes its advice (...) to comparative safety, clinical effectiveness and cost-effectiveness, MSAC supported MBS funding of diagnosis of hypertension using ambulatory bloodpressure monitoring (ABPM) in patients with clinic bloodpressure =140/90 mmHg and =180/110 mmHg on the basis that ABPM is the accepted gold standard for the diagnosis of highbloodpressure in primary care. MSAC accepted that ABPM was cost-effective, but advised that the proposed fee should not include the cost of the consumables. MSAC was concerned
of the antihypertensive medicine.We compared the intervention of discontinuing or reducing antihypertensive medication to usual treatment using mean differences (MD) and 95% confidence intervals (95% CIs) for continuous variables and we used Peto odds ratios (ORs) and 95% CI for binary variables. Our primary outcomes included: mortality, myocardial infarction, development of adverse drug reactions or adverse drug withdrawal reactions. Secondary outcomes included: bloodpressure, hospitalisation, stroke, success (...) certainty of evidence), for myocardial infarction 1.86 (95% CI 0.19 to 17.98; very low certainty of evidence) and for stroke 1.44 (95% CI 0.25 to 8.35; low certainty of evidence). Bloodpressure was higher in the discontinuation group than the continuation group (systolic bloodpressure: MD = 9.75 mmHg, 95% CI 7.33 to 12.18; and diastolic bloodpressure: MD = 3.5 mmHg, 95% CI 1.82 to 5.18; low certainty of evidence). For the development of adverse events, meta-analysis was not possible; antihypertensive
% of maternal deaths, whereas in Africa and Asia they contribute to 9% of deaths. Although maternal mortality is much lower in high-income countries than in developing countries, 16% of maternal deaths can be attributed to hypertensivedisorders . In the United States, the rate of preeclampsia increased by 25% between 1987 and 2004 . Moreover, in comparison with women giving birth in 1980, those giving birth in 2003 were at 6.7-fold increased risk of severe preeclampsia . This complication is costly: one (...) Magnesium Concentration and Toxicities Table 3. Antihypertensive Agents Used for Urgent BloodPressure Control in Pregnancy ACOG Family of Sites ACOG Family of Sites American College of Obstetricians and Gynecologists 409 12th Street SW, Washington, DC 20024-2188 Copyright 2020. All rights reserved. | Please Confirm Bulk pricing was not found for item. Please try reloading page. Price Member Price
, angiotensin converting enzyme inhibitor; AHA-ACC, American Heart Association-American College of Cardiology; ARB, angiotensin receptor blocker; BP, bloodpressure; CCB, calcium channel blocker; DBP, diastolic bloodpressure; ESH, European Society of Hypertension; HBPM, home bloodpressure monitoring; SBP, systolic bloodpressure. Table 6. Bloodpressure thresholds for diagnosis of resistant hypertension Description BP threshold Diabetes Systolic BP> 130 mm Hg or diastolic BP> 80 mm Hg High cardiovascular (...) 25, 2019. After the discussions, the guidelines were further revised and ?nalized for anelectronic vote by all 81 members of the HCGC, with > 70% support required for approval of each new guideline. Guidelines for the diagnosis, assessment, prevention, and treatment of hyper- tension in adults and children are published separately. 10 Key Messages Resistant hypertension (RHT) is de?ned as bloodpressure (BP) above target despite 3 or more BP- lowering drugs at optimal doses preferably including
The Diagnosis and Management of Hypertension in the Primary Care Setting Diagnosis and Management of Hypertension (HTN) in Primary Care (2020) - VA/DoD Clinical Practice Guidelines Attention A T users. To access the menus on this page please perform the following steps. 1. Please switch auto forms mode to off. 2. Hit enter to expand a main menu option (Health, Benefits, etc). 3. To enter and activate the submenu links, hit the down arrow. You will now be able to tab or arrow up or down through (...) the submenu options to access/activate the submenu links. Get help from Veterans Crisis Line Locator Contact Search Contact Us Locator Get help from Veterans Crisis Line Search Enter your search text Button to start search More VA More VA Inside VA Budget and Performance Inside the Media Room National Observances Special Events » » » » » Diagnosis and Management of Hypertension (HTN) in Primary Care (2020) VA/DoD Clinical Practice Guidelines Menu Menu Quick Links Enter ZIP code here Enter ZIP code here