Latest & greatest articles for knee replacement

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Top results for knee replacement

1. Effects of Interleukin-1β Inhibition on Incident Hip and Knee Replacement : Exploratory Analyses From a Randomized, Double-Blind, Placebo-Controlled Trial. (Abstract)

Effects of Interleukin-1β Inhibition on Incident Hip and Knee Replacement : Exploratory Analyses From a Randomized, Double-Blind, Placebo-Controlled Trial. Osteoarthritis is a common inflammatory disorder with no disease-modifying therapies. Whether inhibition of interleukin-1β (IL-1β) can reduce the consequences of large joint osteoarthritis is unclear.To determine whether IL-1β inhibition with canakinumab reduces incident total hip or knee replacement (THR/TKR).Exploratory analysis

2020 Annals of Internal Medicine

2. A Randomized Controlled Trial Comparing a Medial Stabilized Total Knee Prosthesis to a Cruciate Retaining and Posterior Stabilized Design: A Report of the Clinical and Functional Outcomes Following Total Knee Replacement Full Text available with Trip Pro

A Randomized Controlled Trial Comparing a Medial Stabilized Total Knee Prosthesis to a Cruciate Retaining and Posterior Stabilized Design: A Report of the Clinical and Functional Outcomes Following Total Knee Replacement A Randomized Controlled Trial Comparing a Medial Stabilized Total Knee Prosthesis to a Cruciate Retaining and Posterior Stabilized Design: A Report of the Clinical and Functional Outcomes Following Total Knee Replacement - PubMed This site needs JavaScript to work properly (...) Retaining and Posterior Stabilized Design: A Report of the Clinical and Functional Outcomes Following Total Knee Replacement , , , , Affiliations Expand Affiliations 1 Department of Surgery, The University of Melbourne, St Vincent's Hospital, Melbourne, Victoria, Australia; Department of Orthopaedics, St Vincent's Hospital, Melbourne, Victoria, Australia. 2 Department of Surgery, The University of Melbourne, St Vincent's Hospital, Melbourne, Victoria, Australia. 3 Department of Mechanical Engineering

2020 EvidenceUpdates

3. Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery

Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes (...) Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Clin J Pain Actions . 2020 May;36(5):352-358. doi: 10.1097/AJP.0000000000000805. Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery , , , , , , , Affiliations Expand Affiliations 1 Department of Health Science and Technology, Center for Sensory-Motor Interaction (SMI). 2 Orthopaedic Research Unit

2020 EvidenceUpdates

4. Joint replacement (primary): hip, knee and shoulder

Joint replacement (primary): hip, knee and shoulder Joint replacement (primary): hip, knee and shoulder NICE guideline Published: 4 June 2020 www.nice.org.uk/guidance/ng157 © NICE 2020. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Your responsibility Your responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising (...) . Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Joint replacement (primary): hip, knee and shoulder (NG157) © NICE 2020. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 39Contents Contents Overview 5 Who is it for? 5 Recommendations 6 1.1 Shared decision

2020 National Institute for Health and Clinical Excellence - Clinical Guidelines

5. Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT Full Text available with Trip Pro

Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you (...) need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Both total and partial knee replacement were effective and offered similar clinical outcomes at 5 years. {{author}} {{($index , , , , , , , , , , , , & . David J Beard 1, * , Loretta J Davies 1 , Jonathan A Cook 2 , Graeme MacLennan 2 , Andrew Price 1 , Seamus Kent 3 , Jemma Hudson 2 , Andrew Carr 1 , Jose Leal 3 , Helen Campbell 3 , Ray Fitzpatrick 3 , Nigel Arden 1 , David Murray 1

2020 NIHR HTA programme

6. The impact of the enhanced recovery pathway and other factors on outcomes and costs following hip and knee replacement: routine data study Full Text available with Trip Pro

The impact of the enhanced recovery pathway and other factors on outcomes and costs following hip and knee replacement: routine data study The impact of the enhanced recovery pathway and other factors on outcomes and costs following hip and knee replacement: routine data study Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation (...) or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Improved outcomes after hip and knee replacement had begun before the implementation of the enhanced recovery pathway and successful implementation of this pathway depends on several aspects. {{author}} {{($index , , , , , , , , , , , , , , , & . Andrew Judge 1, 2, 3, 4, * , Andrew Carr 1 , Andrew Price 1 , Cesar Garriga 1, 4 , Cyrus

2020 NIHR HTA programme

7. Technology-assisted rehabilitation following total knee or hip replacement for people with osteoarthritis: a systematic review and meta-analysis Full Text available with Trip Pro

Technology-assisted rehabilitation following total knee or hip replacement for people with osteoarthritis: a systematic review and meta-analysis Technology-assisted Rehabilitation Following Total Knee or Hip Replacement for People With Osteoarthritis: A Systematic Review and Meta-Analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History (...) be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation BMC Musculoskelet Disord Actions , 20 (1), 506 2019 Nov 3 Technology-assisted Rehabilitation Following Total Knee or Hip Replacement for People With Osteoarthritis: A Systematic Review and Meta-Analysis , , , , Affiliations Expand Affiliations 1 Level

2020 EvidenceUpdates

8. Partial knee replacement could be first choice for some patients with osteoarthritis. (Abstract)

Partial knee replacement could be first choice for some patients with osteoarthritis. The studyBeard D, Davies L, Cook J, et al. The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Lancet 2019;394:746-56.The study was funded by the NIHR Health Technology Assessment Programme (project number 08/14/08).To read the full NIHR Signal, go to https (...) ://discover.dc.nihr.ac.uk/content/signal-000824/partial-knee-replacement-could-be-first-choice-in-some-patients.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

2019 BMJ

9. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations Full Text available with Trip Pro

Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations: Acta Orthopaedica: Vol 0, No 0 | Search in: Journal 6,974 Views 0 CrossRef citations to date Altmetric Articles Consensus statement for perioperative care in total (...) hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS ® ) Society recommendations , , , , , , & Published online: 30 Oct 2019 In this article Articles Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS ® ) Society recommendations Ljungqvist O , Scott M , Fearon K C . Enhanced Recovery After Surgery: a review . JAMA Surg 2017 ; 152(3): 292 – 8 . , , , ). For total hip (THR

2019 ERAS Society

10. The effects of preoperative balance training on balance and functional outcome after total knee replacement: a randomized controlled trial (Abstract)

The effects of preoperative balance training on balance and functional outcome after total knee replacement: a randomized controlled trial To assess the effects of preoperative balance training on the early postoperative balance and functional outcomes after total knee replacement surgery and to test whether an outpatient intervention may be as effective as a domiciliary intervention.This is a three-arm randomized controlled trial.University hospital.Eighty-six individuals were recruited (...) showed no between-group differences and a small effect size (d < 0.5; P = 0.937). Secondary assessments suggested non-significant between-group differences.Preoperative balance training, conducted either as domiciliary or as an outpatient, is an effective approach to enhance early postoperative balance outcome but not the perceived functionality of individuals undergoing total knee replacement.

2019 EvidenceUpdates

11. Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels (Abstract)

Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels Tranexamic acid (TXA) is an antifibrinolytic drug. Topical administration of TXA during total knee arthroplasty (TKA) is favored for certain patients because of concerns about thrombotic complications, despite a lack of supporting literature. We compared local and systemic levels

2019 EvidenceUpdates

12. Self-Warming Blanket Versus Forced-Air Warming in Primary Knee or Hip Replacement: A Randomized Controlled Non-Inferiority Study. (Abstract)

Self-Warming Blanket Versus Forced-Air Warming in Primary Knee or Hip Replacement: A Randomized Controlled Non-Inferiority Study. After primary total knee/hip replacement (TKR or THR respectively) a prosthetic joint infection (PJI) could develop. Hypothermia could raise the risk of infection. Heating by forced-air can disrupt laminar airfl ow in the operation room (OR), potentially raising the risk of infection. We aimed to study non-inferiority of an active self-heating blanket (SHB) compared

2019 Asian journal of anesthesiology Controlled trial quality: uncertain

13. The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Full Text available with Trip Pro

The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Late-stage isolated medial knee osteoarthritis can be treated with total knee replacement (TKR) or partial knee replacement (PKR). There is high variation in treatment choice and little robust evidence to guide selection. The Total or Partial Knee Arthroplasty Trial (TOPKAT) therefore aims to assess (...) the clinical effectiveness and cost-effectiveness of TKR versus PKR in patients with medial compartment osteoarthritis of the knee, and this represents an analysis of the main endpoints at 5 years.Our multicentre, pragmatic randomised controlled trial was done at 27 UK sites. We used a combined expertise-based and equipoise-based approach, in which patients with isolated osteoarthritis of the medial compartment of the knee and who satisfied general requirements for a medial PKR were randomly assigned (1:1

2019 Lancet Controlled trial quality: predicted high

14. The Arthroplasty Candidacy Help Engine tool to select candidates for hip and knee replacement surgery: development and economic modelling Full Text available with Trip Pro

The Arthroplasty Candidacy Help Engine tool to select candidates for hip and knee replacement surgery: development and economic modelling The Arthroplasty Candidacy Help Engine tool to select candidates for hip and knee replacement surgery: development and economic modelling Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation (...) or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} The Oxford hip and knee scores can be used to assess individuals' suitability for surgery, and this study showed that surgery nearly always costs less than £20,000 per QALY. {{author}} {{($index , , , , , , , , , , , , , , , , , , , , , , , , & . Andrew Price 1, * , James Smith 1 , Helen Dakin 2 , Sujin Kang 1 , Peter Eibich 2

2019 NIHR HTA programme

15. Addition of Adductor Canal Block to Periarticular Injection for Total Knee Replacement: A Randomized Trial (Abstract)

Addition of Adductor Canal Block to Periarticular Injection for Total Knee Replacement: A Randomized Trial Periarticular injection is a popular method to control postoperative pain after total knee replacement. An adductor canal block is a sensory block that can also help to alleviate pain after total knee replacement. We hypothesized that the combination of adductor canal block and periarticular injection would allow patients to reach discharge criteria 0.5 day faster than with periarticular

2019 EvidenceUpdates

16. Radiofrequency ablation of genicular nerves prior to total knee replacement has no effect on postoperative pain outcomes: a prospective randomized sham-controlled trial with 6-month follow-up (Abstract)

Radiofrequency ablation of genicular nerves prior to total knee replacement has no effect on postoperative pain outcomes: a prospective randomized sham-controlled trial with 6-month follow-up Refractory chronic knee pain from osteoarthritis (OA) is commonly treated with total knee arthroplasty (TKA). TKA can be associated with severe postoperative pain and persistent postsurgical knee pain. Poorly controlled postoperative pain can negatively effect functional outcomes following TKA (...) , and effective opioid-sparing analgesia is key to the ideal recovery. Genicular nerve radiofrequency ablation (GN-RFA) has been shown in several trials to be clinically effective in patients with severe refractory knee pain from OA. We aimed to assess if preoperative GN-RFA would improve postoperative pain outcomes following TKA.This was a sham-control prospective clinical trial in which blinded participants were randomized to image-guided GN-RFA or a simulated sham procedure 2-6 weeks prior to elective TKA

2019 EvidenceUpdates

17. Perioperative Dietary Restriction of Carbohydrates in the Management of Blood Glucose Levels in Patients Undergoing Total Knee Replacement (Abstract)

Perioperative Dietary Restriction of Carbohydrates in the Management of Blood Glucose Levels in Patients Undergoing Total Knee Replacement Approximately 75% of the US population over 65 years has prediabetes or diabetes. Despite current evidence for the efficacy of carbohydrate restriction in managing blood glucose, this practice has not been implemented as part of routine perioperative blood sugar management. We hypothesize that a carbohydrate reduced hospital diet (CRD) of 135 g/d may improve (...) blood sugar levels following total knee arthroplasty (TKA) compared to a non-carbohydrate reduced hospital diet (NCRD).We randomized non-insulin-dependent prediabetic and diabetic patients undergoing TKA to either an NCRD or a CRD. Sixty-four patients were enrolled in the study and 2 were excluded, leading to 62 patients in the final analysis. The NCRD group included 14 females (47%) and 16 males (53%), with mean age of 68.5 years (±6.3 years). The CRD group included 16 females (50%) and 16 males

2019 EvidenceUpdates

18. Effectiveness of Later-Stage Exercise Programs vs Usual Medical Care on Physical Function and Activity After Total Knee Replacement: A Randomized Clinical Trial Full Text available with Trip Pro

Effectiveness of Later-Stage Exercise Programs vs Usual Medical Care on Physical Function and Activity After Total Knee Replacement: A Randomized Clinical Trial Several functional limitations persist after total knee replacement (TKR). Intensive exercise programs could resolve these limitations but are not well tolerated by many patients until a later stage (>2 months) after surgery. Evidence for exercise at a later stage after TKR is limited.To compare the effectiveness of later-stage exercise (...) germane to knee replacement and additional surveys of physical function. Data were analyzed by linear mixed models and responder analysis.A total of 240 participants (mean [SD] age, 70 [7] years; 61.7% female) were allocated to physical therapy (n = 96), community exercise (n = 96), or control (n = 48). All 3 arms demonstrated clinically important improvement. At 3 months, between-arm analyses for the WOMAC-PF demonstrated no differences between physical therapy and community (-2.2; 98.3% CI, -4.5

2019 EvidenceUpdates

19. The Effect of Prosthetic Design and Polyethylene Type on the Risk of Revision for Infection in Total Knee Replacement: An Analysis of 336,997 Prostheses from the Australian Orthopaedic Association National Joint Replacement Registry (Abstract)

The Effect of Prosthetic Design and Polyethylene Type on the Risk of Revision for Infection in Total Knee Replacement: An Analysis of 336,997 Prostheses from the Australian Orthopaedic Association National Joint Replacement Registry Periprosthetic infection following total knee replacement remains alarmingly frequent, is devastating for patients, and is an increasingly substantial public health burden. While both the prosthetic design elements and type of polyethylene used in total knee (...) replacement can independently affect survivorship of the prosthesis, their influence on the risk of revision for infection is unknown. Therefore, we examined the effects of total knee prosthetic design and type of polyethylene bearing on the long-term revision risk for nonacute infection following total knee replacement by comparing 4 different cohorts: patients who had minimally stabilized total knee prostheses with crosslinked polyethylene (XLPE) bearing surfaces, minimally stabilized total knee

2019 EvidenceUpdates

20. Knee replacement. (Abstract)

Knee replacement. Knee replacement surgery is one of the most commonly done and cost-effective musculoskeletal surgical procedures. The numbers of cases done continue to grow worldwide, with substantial variation in utilisation rates across regions and countries. The main indication for surgery remains painful knee osteoarthritis with reduced function and quality of life. The threshold for intervention is not well defined, and is influenced by many factors including patient and surgeon (...) preference. Most patients have a very good clinical outcome after knee replacement, but multiple studies have reported that 20% or more of patients do not. So despite excellent long-term survivorship, more work is required to enhance this procedure and development is rightly focused on increasing the proportion of patients who have successful pain relief after surgery. Changing implant design has historically been a target for improving outcome, but there is greater recognition that improvements can

2018 Lancet