Latest & greatest articles for pain

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pain or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on pain and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for pain

1. Chronic Pelvic Pain

Chronic Pelvic Pain Chronic Pelvic Pain | ACOG Clinical Guidance Journals & Publications Patient Education Topics Featured Clinical Topics Hi, Featured Clinical Topics Clinical Guidance Chronic Pelvic Pain Practice Bulletin Number 218 March 2020 Jump to Resources Share By reading this page you agree to ACOG's Terms and Conditions. . Log in to read more This content is only available to members and subscribers. Nonmembers: Subscribe now to access exclusive ACOG Clinical content, including: ACOG

2020 American College of Obstetricians and Gynecologists

2. Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain Full Text available with Trip Pro

Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library of Medicine National Center (...) Link Copy Actions Cite Share Permalink Copy Page navigation Clin J Pain Actions . 2020 Jun;36(6):458-462. doi: 10.1097/AJP.0000000000000821. Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain , , , , , , , , , , , Affiliations Expand Affiliations 1 Emergency Department, Fattouma Bourguiba University Hospital. 2 Research Laboratory LR12SP18, University of Monastir. 3 Emergency Department, Farhat Hached University Hospital. 4 Emergency Department

2020 EvidenceUpdates

3. The effect of manual therapy to the thoracic spine on pain-free grip and sympathetic activity in patients with lateral epicondylalgia humeri. A randomized, sample sized planned, placebo-controlled, patient-blinded monocentric trial Full Text available with Trip Pro

The effect of manual therapy to the thoracic spine on pain-free grip and sympathetic activity in patients with lateral epicondylalgia humeri. A randomized, sample sized planned, placebo-controlled, patient-blinded monocentric trial The Effect of Manual Therapy to the Thoracic Spine on Pain-Free Grip and Sympathetic Activity in Patients With Lateral Epicondylalgia Humeri. A Randomized, Sample Sized Planned, Placebo-Controlled, Patient-Blinded Monocentric Trial - PubMed This site needs JavaScript (...) ? Report format: Send at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation BMC Musculoskelet Disord Actions . 2020 Mar 24;21(1):186. doi: 10.1186/s12891-020-3175-y. The Effect of Manual Therapy to the Thoracic Spine on Pain-Free Grip and Sympathetic

2020 EvidenceUpdates

4. Comparing the analgesic effect of intravenous paracetamol with morphine on patients with renal colic pain: A meta-analysis of randomized controlled studies

Comparing the analgesic effect of intravenous paracetamol with morphine on patients with renal colic pain: A meta-analysis of randomized controlled studies Comparing the Analgesic Effect of Intravenous Paracetamol With Morphine on Patients With Renal Colic Pain: A Meta-Analysis of Randomized Controlled Studies - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features (...) software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Review Am J Emerg Med Actions . 2020 Apr 2;S0735-6757(20)30217-5. doi: 10.1016/j.ajem.2020.03.061. Online ahead of print. Comparing the Analgesic Effect of Intravenous Paracetamol With Morphine on Patients With Renal Colic Pain: A Meta-Analysis of Randomized Controlled Studies , , , Affiliations Expand Affiliations 1 Department

2020 EvidenceUpdates

5. Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery

Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes (...) Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Clin J Pain Actions . 2020 May;36(5):352-358. doi: 10.1097/AJP.0000000000000805. Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery , , , , , , , Affiliations Expand Affiliations 1 Department of Health Science and Technology, Center for Sensory-Motor Interaction (SMI). 2 Orthopaedic Research Unit

2020 EvidenceUpdates

6. Opioid-induced Euphoria Among Emergency Department Patients With Acute Severe Pain: An Analysis of Data From a Randomized Trial

Opioid-induced Euphoria Among Emergency Department Patients With Acute Severe Pain: An Analysis of Data From a Randomized Trial Opioid-induced Euphoria Among Emergency Department Patients With Acute Severe Pain: An Analysis of Data From a Randomized Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health (...) Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Acad Emerg Med Actions . 2020 Mar 27. doi: 10.1111/acem.13946. Online ahead of print. Opioid-induced Euphoria Among Emergency Department Patients With Acute Severe Pain: An Analysis of Data From a Randomized Trial , , , , Affiliations Expand Affiliations 1 From the, Department of Emergency Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY. 2

2020 EvidenceUpdates

7. Two Weeks of Wearing a Knee Brace Compared With Minimal Intervention on Kinesiophobia at 2 and 6 Weeks in People With Patellofemoral Pain: A Randomized Controlled Trial

Two Weeks of Wearing a Knee Brace Compared With Minimal Intervention on Kinesiophobia at 2 and 6 Weeks in People With Patellofemoral Pain: A Randomized Controlled Trial Two Weeks of Wearing a Knee Brace Compared With Minimal Intervention on Kinesiophobia at 2 and 6 Weeks in People With Patellofemoral Pain: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several (...) for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Arch Phys Med Rehabil Actions . 2020 Apr;101(4):613-623. doi: 10.1016/j.apmr.2019.10.190. Epub 2019 Dec 10. Two Weeks of Wearing a Knee Brace Compared With Minimal Intervention on Kinesiophobia at 2 and 6 Weeks in People With Patellofemoral Pain: A Randomized Controlled Trial , , , , Affiliations Expand

2020 EvidenceUpdates

8. Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial Full Text available with Trip Pro

Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes (...) Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation JAMA Netw Open Actions . 2020 Mar 2;3(3):e200287. doi: 10.1001/jamanetworkopen.2020.0287. Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial , , , , , , , , , , , , Affiliations Expand Affiliations 1 Durham VA Health Care System, Durham, North Carolina. 2 Department of Psychiatry and Behavioral

2020 EvidenceUpdates

9. New procedure of high-frequency repetitive transcranial magnetic stimulation for central neuropathic pain: a placebo-controlled randomized crossover study

New procedure of high-frequency repetitive transcranial magnetic stimulation for central neuropathic pain: a placebo-controlled randomized crossover study New Procedure of High-Frequency Repetitive Transcranial Magnetic Stimulation for Central Neuropathic Pain: A Placebo-Controlled Randomized Crossover Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features (...) software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Pain Actions . 2020 Apr;161(4):718-728. doi: 10.1097/j.pain.0000000000001760. New Procedure of High-Frequency Repetitive Transcranial Magnetic Stimulation for Central Neuropathic Pain: A Placebo-Controlled Randomized Crossover Study , , , , , , , Affiliations Expand Affiliations 1 Laboratoire Intégration Centrale de la Douleur chez

2020 EvidenceUpdates

10. Platelet-rich Plasma or Autologous Blood Do Not Reduce Pain or Improve Function in Patients with Lateral Epicondylitis: A Randomized Controlled Trial

Platelet-rich Plasma or Autologous Blood Do Not Reduce Pain or Improve Function in Patients with Lateral Epicondylitis: A Randomized Controlled Trial Platelet-rich Plasma or Autologous Blood Do Not Reduce Pain or Improve Function in Patients With Lateral Epicondylitis: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features (...) software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Clin Orthop Relat Res Actions . 2020 Feb 25. doi: 10.1097/CORR.0000000000001185. Online ahead of print. Platelet-rich Plasma or Autologous Blood Do Not Reduce Pain or Improve Function in Patients With Lateral Epicondylitis: A Randomized Controlled Trial , , , , Affiliations Expand Affiliation 1 L. Linnanmäki, K. Kanto, J. Lehtinen, Tays

2020 EvidenceUpdates

11. Analgesic Efficacy and Adverse Effects of Meperidine in Managing Postoperative or Labor Pain: A Narrative Review of Randomized Controlled Trials

Analgesic Efficacy and Adverse Effects of Meperidine in Managing Postoperative or Labor Pain: A Narrative Review of Randomized Controlled Trials Analgesic Efficacy and Adverse Effects of Meperidine in Managing Postoperative or Labor Pain: A Narrative Review of Randomized Controlled Trials - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily (...) Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Pain Physician Actions . 2020 Mar;23(2):175-201. Analgesic Efficacy and Adverse Effects of Meperidine in Managing Postoperative or Labor Pain: A Narrative Review of Randomized Controlled Trials , Affiliations Expand Affiliation 1 Laboratory and Clinical Research Institute for Pain, Dept of Anesthesiology, The University of Hong Kong. PMID

2020 EvidenceUpdates

12. End of Life Care in Frailty: Pain

End of Life Care in Frailty: Pain End of Life Care in Frailty: Pain | British Geriatrics Society Toggle main menu visibility Search Search Search Resources (menu position rule) , Date Published: 12 May 2020 Last updated: 12 May 2020 The aim of this guidance series is to support clinicians and others to consider the needs of frail older people as they move towards the end of their lives and help them to provide high quality care. This chapter examines the management of pain in older people (...) living with frailty at the end of life. Please to view the other chapters in this series. While 80% of people will experience pain at some point as they age, and for more than 60% of people it will be moderate or severe. Pain should not be seen as a ‘normal’ part of ageing to simply ‘put up with’ or ignore. Managing pain in older people living with frailty brings challenges. Older people experience and perceive pain differently for both physiological and psychological . 1 Pain thresholds are also

2020 British Geriatrics Society

13. Effect of Flurbiprofen and S-Flurbiprofen Patches on Multimodal Pain Management After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial

Effect of Flurbiprofen and S-Flurbiprofen Patches on Multimodal Pain Management After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial Effect of Flurbiprofen and S-Flurbiprofen Patches on Multimodal Pain Management After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features (...) software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation J Arthroplasty Actions . 2020 Apr 10;S0883-5403(20)30336-3. doi: 10.1016/j.arth.2020.04.006. Online ahead of print. Effect of Flurbiprofen and S-Flurbiprofen Patches on Multimodal Pain Management After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial , , , , , Affiliations Expand Affiliations 1 Department

2020 EvidenceUpdates

14. Complementary Saphenous Nerve Block to Intra-Articular Analgesia Reduces Pain After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial Full Text available with Trip Pro

Complementary Saphenous Nerve Block to Intra-Articular Analgesia Reduces Pain After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial Complementary Saphenous Nerve Block to Intra-Articular Analgesia Reduces Pain After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features (...) software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation J Arthroplasty Actions . 2020 Jun;35(6S):S168-S172. doi: 10.1016/j.arth.2020.03.010. Epub 2020 Mar 12. Complementary Saphenous Nerve Block to Intra-Articular Analgesia Reduces Pain After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial , , Affiliations Expand Affiliation 1 Institute of Orthopaedics "Carlos E

2020 EvidenceUpdates

15. Effect of Biomechanical Footwear on Knee Pain in People With Knee Osteoarthritis: The BIOTOK Randomized Clinical Trial. (Abstract)

Effect of Biomechanical Footwear on Knee Pain in People With Knee Osteoarthritis: The BIOTOK Randomized Clinical Trial. Individually calibrated biomechanical footwear therapy may improve pain and physical function in people with symptomatic knee osteoarthritis, but the benefits of this therapy are unclear.To assess the effect of a biomechanical footwear therapy vs control footwear over 24 weeks of follow-up.Randomized clinical trial conducted at a Swiss university hospital. Participants (N (...) pain at 24 weeks of follow-up assessed with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscore standardized to range from 0 (no symptoms) to 10 (extreme symptoms). The secondary outcomes included WOMAC physical function and stiffness subscores and the WOMAC global score, all ranging from 0 (no symptoms) to 10 (extreme symptoms) at 24 weeks of follow-up, and serious adverse events.Among the 220 randomized participants (mean age, 65.2 years [SD, 9.3 years]; 104

2020 JAMA

16. Covid-19: Pain

Covid-19: Pain Pain Management during the COVID-19 Pandemic - eanpages COVID-19 May 13, 2020 COVID-19 May 13, 2020 COVID-19 May 6, 2020 COVID-19 May 6, 2020 COVID-19 May 13, 2020 COVID-19 May 13, 2020 COVID-19 May 6, 2020 COVID-19 May 6, 2020 Executive Page May 1, 2020 Executive Page April 1, 2020 Executive Page March 1, 2020 Executive Page February 1, 2020 Country of the Month May 1, 2020 Country of the Month April 5, 2020 Country of the Month March 1, 2020 Country of the Month February 1 (...) societies reports January 2, 2020 Surveys April 10, 2020 Surveys October 7, 2019 Forum April 1, 2016 Forum March 1, 2016 Forum March 1, 2016 Forum February 1, 2016 Uncategorized May 2, 2020 Uncategorized May 1, 2020 Uncategorized May 1, 2020 Uncategorized April 29, 2020 Pain Management during the COVID-19 Pandemic April 8, 2020 Due to the CoVID-19 pandemic spread, most outpatient facilities have been strictly regulated, thus making it difficult for many patients suffering from chronic pain to access

2020 European Academy of Neurology

17. Opioid Treatments for Chronic Pain

Opioid Treatments for Chronic Pain Opioid Treatments for Chronic Pain Comparative Effectiveness Review Number 229 R Comparative Effectiveness Review Number 229 Opioid Treatments for Chronic Pain Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahrq.gov Contract No. 290-2015-00009-I Prepared by: Pacific Northwest Evidence-based Practice Center Portland, OR Investigators: Roger Chou, M.D. Daniel Hartung (...) , Pharm.D. Judith Turner, Ph.D. Ian Blazina, M.P.H. Brian Chan, M.D. Ximena Levander, M.D. Marian McDonagh, Pharm.D. Shelley Selph, M.D., M.P.H. Rongwei Fu, Ph.D. Miranda Pappas, M.A. AHRQ Publication No. 20-EHC011 April 2020 ii Key Messages Purpose of Review To assess the effectiveness and harms of opioid therapy for chronic noncancer pain, alternative opioid dosing strategies, and risk mitigation strategies Key Messages • Opioids are associated with small improvements versus placebo in pain

2020 Effective Health Care Program (AHRQ)

18. Nonopioid Pharmacologic Treatments for Chronic Pain

Nonopioid Pharmacologic Treatments for Chronic Pain Nonopioid Pharmacologic Treatments for Chronic Pain Comparative Effectiveness Review Number 228 R Comparative Effectiveness Review Number 228 Nonopioid Pharmacologic Treatments for Chronic Pain Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahrq.gov Contract No. 290-2015-00009-I Prepared by: Pacific Northwest Evidence-based Practice Center Portland (...) , OR Investigators: Marian S. McDonagh, Pharm.D. Shelley S. Selph, M.D., M.P.H. David I. Buckley, M.D., M.P.H. Rebecca S. Holmes, M.D., M.S. Kimberly Mauer, M.D. Shaun Ramirez, M.P.H. Frances C. Hsu, M.S. Tracy Dana, M.L.S. Rochelle Fu, Ph.D. Roger Chou, M.D. AHRQ Publication No. 20-EHC010 April 2020 ii Key Messages Purpose of Review Evaluate the benefits and harms of nonopioid drugs in randomized controlled trials of patients with specific types of chronic pain, considering the effects on pain, function

2020 Effective Health Care Program (AHRQ)

19. Noninvasive Nonpharmacological Treatment for Chronic Pain

Noninvasive Nonpharmacological Treatment for Chronic Pain Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update Comparative Effectiveness Review Number 227 R Comparative Effectiveness Review Number 227 Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahrq.gov Contract No. 290-2015 (...) for common chronic pain conditions. Key Messages • Interventions that improved function and/or pain for =1 month: o Low back pain: Exercise, psychological therapy, spinal manipulation, low-level laser therapy, massage, mindfulness-based stress reduction, yoga, acupuncture, multidisciplinary rehabilitation (MDR) o Neck pain: Exercise, low-level laser, mind-body practices, massage, acupuncture o Knee osteoarthritis: Exercise, cognitive behavioral therapy (CBT) o Hip osteoarthritis: Exercise, manual

2020 Effective Health Care Program (AHRQ)

20. Treatments for Chronic Pain

Treatments for Chronic Pain Treatments for Chronic Pain | Effective Health Care Program Search Effective Health Care website Submit search Toggle navigation Select site to search Search Effective Health Care website Submit search » » » Treatments for Chronic Pain Chronic pain affects millions of adults in the United States. It is the leading cause of disability and significantly impacts physical and mental functioning and quality of life. Chronic pain is often defined as pain lasting 3 months (...) or longer or persisting past the normal time for tissue healing. HHS is committed to the promotion of evidence-based approaches to safe and appropriate treatment of chronic pain. The AHRQ Evidence-based Practice Center Program, on request from the U.S. Centers for Disease Control and Prevention, has conducted a comprehensive synthesis of the recent evidence from the peer-reviewed literature on the effectiveness and harms of noninvasive treatments for chronic noncancer pain. The current state

2020 Effective Health Care Program (AHRQ)