Latest & greatest articles for pulmonary embolism

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Top results for pulmonary embolism

1. Are Recanalization Interventions Effective and Safe in the Treatment of Acute Pulmonary Embolism? Full Text available with Trip Pro

-sided heart strain. x 3 Goldhaber, S.Z., Visani, L., and De Rosa, M. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet . 1999 ; 353 : 1386–1389 | | | | | , x 4 Kearon, C., Akl, E.A., Ornelas, J. et al. Antithrombotic therapy for VTE disease: CHEST guideline expert panel report. Chest . 2016 ; 149 : 315–352 | | | | | Full-dose thrombolysis may be beneficial in hemodynamically unstable patients with pulmonary embolism (...) , but this therapy increases the risk of major bleeding. x 4 Kearon, C., Akl, E.A., Ornelas, J. et al. Antithrombotic therapy for VTE disease: CHEST guideline expert panel report. Chest . 2016 ; 149 : 315–352 | | | | | , x 5 Meyer, G., Vicaut, E., Danays, T. et al. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med . 2014 ; 370 : 1402–1411 | | | , x 6 Konstantinides, S.V., Torbicki, A., Agnelli, G. et al. 2014 ESC guidelines on the diagnosis and management of acute pulmonary

2020 Annals of Emergency Medicine Systematic Review Snapshots

2. YEARS Algorithm Versus Wells' Score: Predictive Accuracies in Pulmonary Embolism Based on the Gold Standard CT Pulmonary Angiography

YEARS Algorithm Versus Wells' Score: Predictive Accuracies in Pulmonary Embolism Based on the Gold Standard CT Pulmonary Angiography YEARS Algorithm Versus Wells' Score: Predictive Accuracies in Pulmonary Embolism Based on the Gold Standard CT Pulmonary Angiography - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced (...) characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Crit Care Med Actions 2020 Feb 19 [Online ahead of print] YEARS Algorithm Versus Wells' Score: Predictive Accuracies in Pulmonary Embolism Based on the Gold Standard CT Pulmonary Angiography , , , , , , , Affiliations Expand Affiliations 1 Department of Anesthesia, Beni

2020 EvidenceUpdates

3. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS)

2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) Options

2020 European Respiratory Society

4. Interventional Therapies for Acute Pulmonary Embolism: Current Status and Principles for the Development of Novel Evidence: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

Interventional Therapies for Acute Pulmonary Embolism: Current Status and Principles for the Development of Novel Evidence: A Scientific Statement From the American Heart Association Interventional Therapies for Acute Pulmonary Embolism: Current Status and Principles for the Development of Novel Evidence: A Scientific Statement From the American Heart Association | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search December 2019 November 2019 October (...) 2019 September 2019 August 2019 July 2019 June 2019 May 2019 April 2019 March 2019 February 2019 January 2019 This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. Free Access article Share on Jump to Free Access article Interventional Therapies for Acute Pulmonary Embolism: Current Status and Principles for the Development of Novel Evidence: A Scientific Statement From the American Heart Association , MD, MPH, FAHA, Chair , MD, FAHA, Vice Chair , MD, MSc

2019 American Heart Association

5. Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability. Full Text available with Trip Pro

-PTP and a d-dimer level of less than 1000 ng per milliliter or with a moderate C-PTP and a d-dimer level of less than 500 ng per milliliter. All other patients underwent chest imaging (usually computed tomographic pulmonary angiography). If pulmonary embolism was not diagnosed, patients did not receive anticoagulant therapy. All patients were followed for 3 months to detect venous thromboembolism.A total of 2017 patients were enrolled and evaluated, of whom 7.4% had pulmonary embolism on initial (...) not receive anticoagulant therapy, 1 patient (0.05%; 95% CI, 0.01 to 0.30) had venous thromboembolism. Our diagnostic strategy resulted in the use of chest imaging in 34.3% of patients, whereas a strategy in which pulmonary embolism is considered to be ruled out with a low C-PTP and a d-dimer level of less than 500 ng per milliliter would result in the use of chest imaging in 51.9% (difference, -17.6 percentage points; 95% CI, -19.2 to -15.9).A combination of a low C-PTP and a d-dimer level of less than

2019 NEJM

6. Thrombolytics for Patients with Acute or Massive Pulmonary Embolisms: Clinical Effectiveness and Guidelines

Thrombolytics for Patients with Acute or Massive Pulmonary Embolisms: Clinical Effectiveness and Guidelines Thrombolytics for Patients with Acute or Massive Pulmonary Embolisms: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Thrombolytics for Patients with Acute or Massive Pulmonary Embolisms: Clinical Effectiveness and Guidelines Thrombolytics for Patients with Acute or Massive Pulmonary Embolisms: Clinical Effectiveness and Guidelines Last updated: August 27 (...) , 2019 Project Number: RB1385-000 Product Line: Research Type: Drug Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of thrombolytics for the treatment of adults with acute or emergent massive pulmonary embolism? What are the evidence-based guidelines regarding thrombolytics in managing adult patients with acute or emergent massive pulmonary embolism? Key Message Three systematic reviews with meta-analyses, seven meta-analyses, five randomized

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

7. Diagnosis and Management of Acute Pulmonary Embolism Full Text available with Trip Pro

Diagnosis and Management of Acute Pulmonary Embolism 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) | European Heart Journal | Oxford Academic ') We use cookies to enhance your experience on our website.By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Search Account Menu Menu Navbar Search Filter Mobile Microsite (...) Search Term Close search filter search input Article Navigation Close mobile search navigation Article Navigation Article Contents Article Navigation 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC) Stavros V Konstantinides Chairperson Germany/Greece Corresponding authors: Stavros

2019 European Society of Cardiology

8. Could the YEARS algorithm be used to exclude pulmonary embolism during pregnancy? Data from the CT-PE-pregnancy study (Abstract)

Could the YEARS algorithm be used to exclude pulmonary embolism during pregnancy? Data from the CT-PE-pregnancy study The recently proposed YEARS algorithm was shown to safely exclude pulmonary embolism (PE) and reduce the use of computed tomography pulmonary angiography (CTPA) among pregnant women with suspected PE. Our aim was to externally validate this finding.We performed a post hoc analysis of a prospective management outcome study for PE diagnosis in pregnant women. PE was diagnosed

2019 EvidenceUpdates

9. Hospital volume and outcomes for acute pulmonary embolism: multinational population based cohort study. Full Text available with Trip Pro

Hospital volume and outcomes for acute pulmonary embolism: multinational population based cohort study. To evaluate the association between experience in the management of acute pulmonary embolism, reflected by hospital case volume, and mortality.Multinational population based cohort study using data from the Registro Informatizado de la Enfermedad TromboEmbólica (RIETE) registry between 1 January 2001 and 31 August 2018.353 hospitals in 16 countries.39 257 consecutive patients with confirmed (...) diagnosis of acute symptomatic pulmonary embolism.Pulmonary embolism related mortality within 30 days after diagnosis of the condition.Patients with acute symptomatic pulmonary embolism admitted to high volume hospitals (>40 pulmonary embolisms per year) had a higher burden of comorbidities. A significant inverse association was seen between annual hospital volume and pulmonary embolism related mortality. Admission to hospitals in the highest quarter (that is, >40 pulmonary embolisms per year

2019 BMJ

10. Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism: A Prospective Cohort Study. (Abstract)

Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism: A Prospective Cohort Study. Pulmonary embolism (PE) is associated with increased risk for ischemic stroke, but the underlying mechanism remains unclear. The authors hypothesized that paradoxical embolism through patent foramen ovale (PFO) should be the main mechanism.To determine the frequency of recent ischemic stroke in patients with symptomatic PE according to whether PFO was detected.Prospective cohort study (...) was more frequent in the PFO group than in the non-PFO group (9 of 42 patients [21.4%] vs. 15 of 273 patients [5.5%]; difference in proportions, 15.9 percentage points [95% CI, 4.7 to 30.7 percentage points]).Because of inconclusive contrast TTE or MRI, 46 patients were excluded from analysis.Frequency of recent ischemic stroke in patients with symptomatic PE was higher in patients with PFO than in those without PFO. This finding supports the hypothesis that paradoxical embolism is an important

2019 Annals of Internal Medicine

11. A novel electrocardiographic parameter for diagnosis of acute pulmonary embolism: RS time: RS time in acute pulmonary embolism (Abstract)

A novel electrocardiographic parameter for diagnosis of acute pulmonary embolism: RS time: RS time in acute pulmonary embolism Pulmonary embolism (PE) is one of the leading causes of cardiovascular mortality worldwide. Electrocardiography (ECG) may provide useful information for patients with acute PE. In this study, we aimed to investigate the diagnostic value of the QRS duration and RS time in inferolateral leads in patients admitted to the emergency department, and pre-diagnosed with acute (...) PE.We retrospectively enrolled 136 consecutive patients, admitted to the emergency department, pre-diagnosed with the clinical suspicion of acute PE, and underwent computerized tomographic pulmonary angiography (CTPA) to confirm the PE diagnosis. The study subjects were divided into two groups according to the presence or absence of PE, and the independent predictors of PE were investigated.Sixty-eight patients (50%) had PE. Patients with PE had a longer RS time. Among the ECG parameters, only RS

2019 EvidenceUpdates

12. Tofacitinib (Xeljanz): restriction of 10 mg twice-daily dose in patients at high risk of pulmonary embolism while safety review is ongoing

Tofacitinib (Xeljanz): restriction of 10 mg twice-daily dose in patients at high risk of pulmonary embolism while safety review is ongoing Tofacitinib (Xeljanz▼): restriction of 10 mg twice-daily dose in patients at high risk of pulmonary embolism while safety review is ongoing - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Tofacitinib (Xeljanz▼): restriction of 10 mg twice-daily dose in patients at high risk of pulmonary embolism while safety review is ongoing Following (...) observation in a clinical study of an increased risk of pulmonary embolism and overall mortality with tofacitinib 10 mg twice-daily in rheumatoid arthritis, a safety review has started and new contraindications introduced. The 10 mg twice-daily dose of tofacitinib (authorised for ulcerative colitis) must not be used in patients at high risk of pulmonary embolism. Published 17 May 2019 From: Therapeutic area: , , , A European safety review of tofacitinib ( ) has begun following results from an ongoing

2019 MHRA Drug Safety Update

13. Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism. Full Text available with Trip Pro

Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism. Pulmonary embolism is one of the leading causes of maternal death in the Western world. Because of the low specificity and sensitivity of the d-dimer test, all pregnant women with suspected pulmonary embolism undergo computed tomographic (CT) pulmonary angiography or ventilation-perfusion scanning, both of which involve radiation exposure to the mother and fetus. Whether a pregnancy-adapted algorithm could be used (...) to safely avoid diagnostic imaging in pregnant women with suspected pulmonary embolism is unknown.In a prospective study involving pregnant women with suspected pulmonary embolism, we assessed three criteria from the YEARS algorithm (clinical signs of deep-vein thrombosis, hemoptysis, and pulmonary embolism as the most likely diagnosis) and measured the d-dimer level. Pulmonary embolism was ruled out if none of the three criteria were met and the d-dimer level was less than 1000 ng per milliliter

2019 NEJM

14. The Prognostic Value of Renal Function in Acute Pulmonary Embolism-A Multi-Centre Cohort Study (Abstract)

The Prognostic Value of Renal Function in Acute Pulmonary Embolism-A Multi-Centre Cohort Study  Haemodynamic alterations caused by acute pulmonary embolism (PE) may affect multi-organ function including kidneys. This multi-centre, multinational cohort study aimed to validate the prognostic significance of estimated glomerular filtration rate (eGFR) and its potential additive value to the current PE risk assessment algorithms. The post hoc analysis of pooled prospective cohort studies: 2,845

2019 EvidenceUpdates

15. Inhaled nitric oxide to treat intermediate risk pulmonary embolism: A multicenter randomized controlled trial. Full Text available with Trip Pro

Inhaled nitric oxide to treat intermediate risk pulmonary embolism: A multicenter randomized controlled trial. To test the hypothesis that adjunctive inhaled NO would improve RV function and viability in acute PE.This was a randomized, placebo-controlled, double blind trial conducted at four academic hospitals. Eligible patients had acute PE without systemic arterial hypotension but had RV dysfunction and a treatment plan of standard anticoagulation. Subjects received either oxygen plus

2019 Nitric oxide : biology and chemistry Controlled trial quality: predicted high

16. Pulmonary embolism

% at 5 years, and 30% at 10 years. The frequency of recurrence does not appear to depend on the clinical presentation of the first event (that is, whether it was a DVT or PE), but recurrent VTE is likely to occur in the same clinical form as the first event [ ]. Diagnosis Diagnosis of pulmonary embolism When to suspect When should I suspect pulmonary embolism? Suspect pulmonary embolism (PE) in a person with dyspnoea, tachypnoea, pleuritic chest pain, and/or features of deep vein thrombosis (DVT (...) of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) [ ]. The symptoms and signs of pulmonary embolism (PE) are based on the NICE guidelines [ ; ]. In a study identified in the ESC guideline, the clinial characteristics of people with suspected (n = 528) and confirmed (n = 1880) PE in the emergency department were [ ]: Dyspnoea — 51% and 50%, respectively. Pleuritic chest pain — 28% and 39%, respectively

2019 NICE Clinical Knowledge Summaries

17. Increasing Safe Outpatient Management of Emergency Department Patients With Pulmonary Embolism: A Controlled Pragmatic Trial. (Abstract)

Increasing Safe Outpatient Management of Emergency Department Patients With Pulmonary Embolism: A Controlled Pragmatic Trial. Many low-risk patients with acute pulmonary embolism (PE) in the emergency department (ED) are eligible for outpatient care but are hospitalized nonetheless. One impediment to home discharge is the difficulty of identifying which patients can safely forgo hospitalization.To evaluate the effect of an integrated electronic clinical decision support system (CDSS

2018 Annals of Internal Medicine

18. Accuracy and Interobserver Reliability of the Simplified Pulmonary Embolism Severity Index Versus the Hestia Criteria for Patients With Pulmonary Embolism (Abstract)

Accuracy and Interobserver Reliability of the Simplified Pulmonary Embolism Severity Index Versus the Hestia Criteria for Patients With Pulmonary Embolism The objective was to assess and compare the accuracy and interobserver reliability of the simplified Pulmonary Embolism Severity Index (sPESI) and the Hestia criteria for predicting short-term mortality in patients with pulmonary embolism (PE).This prospective cohort study evaluated consecutive eligible adults with PE diagnosed

2018 EvidenceUpdates

19. Can Echocardiography Be Used to Diagnose Pulmonary Embolism at the Bedside?

Can Echocardiography Be Used to Diagnose Pulmonary Embolism at the Bedside? TAKE-HOME MESSAGE When pretest probability for pulmonary embolism is high, abnormalities in right ventricular function detected on echocardiogram strongly support the diagnosis; however, a normal echocardiogram cannot be used to rule out pulmonary embolism. Can Echocardiography Be Used to Diagnose Pulmonary Embolism at the Bedside? EBEM Commentators Robert R. Ehrman, MD Mark J. Favot, MD Department of Emergency Medicine (...) by cardiologists, and 1 unclear)andatthepointofcarein 7 studies; 7 studies were con- ducted solely in the ED. The authors identi?ed 9 unique echocardiographic signs of pulmo- nary embolism, as well as the unde?ned ?nding of “right-sided heart strain.” Overall, the signs of pulmonary embolism were moder- atelyspeci?c(range61%to99%)but poorly sensitive (range 5% to 80%). Test characteristics were slightly improved when echocardiograms were performed by physicians. In the pooled and subgroup analyses, McConnell’s

2018 Annals of Emergency Medicine Systematic Review Snapshots

20. What Is the Best Imaging Study to Rule Out Pulmonary Embolism in Pregnancy? (SRS diagnosis)

is gener- ally more readily available in the ED and is read faster, with better interobserver agreement in inter- pretation compared with lung scintigraphy. 8 The Appropriate Use Criteria for Ventilation- Perfusion Imaging in Pulmonary Embolism working group 9 offers additional practical pointers. For pregnant patients for whom pulmonary embolism is suspected and for whom the chest radiograph result is normal, lung scintigraphy is a good choice because it limits the radiation to the mother (...) . If, on the other hand, the chest radiograph is grossly abnormal, then lung scinti- graphy would not be appropriate because it would likely be inconclusive owing to the inherent mismatch. The ability of CT pulmonary angiography to elucidate an alternative diagnosis, which may occur up to 33% of the time, may also be bene?cial. 10 This review suggests that both CT pulmonary angiography and lung scintigraphy may be useful in the evaluation of suspected pulmonary embolism in the pregnant patient. 1. Whiting PF

2018 Annals of Emergency Medicine Systematic Review Snapshots